M
Marcio S. Rocha
Researcher at Universidade Federal de Viçosa
Publications - 68
Citations - 1255
Marcio S. Rocha is an academic researcher from Universidade Federal de Viçosa. The author has contributed to research in topics: Optical tweezers & Persistence length. The author has an hindex of 18, co-authored 63 publications receiving 958 citations. Previous affiliations of Marcio S. Rocha include Universidade Federal de Minas Gerais.
Papers
More filters
Journal ArticleDOI
Towards absolute calibration of optical tweezers.
Nathan B. Viana,Marcio S. Rocha,Oscar N. Mesquita,A. Mazolli,P. A. Maia Neto,H. M. Nussenzveig +5 more
TL;DR: In this paper, the results of the Mie-Debye-spherical aberration (MDSA) theory were investigated for absolute force calibration of optical tweezers, and the results asymptotically approach geometrical optics in the mean over size intervals, as they should, and this already happens for size parameters not much larger than unity.
Journal ArticleDOI
Absolute calibration of optical tweezers
Nathan B. Viana,A. Mazolli,P. A. Maia Neto,H. M. Nussenzveig,Marcio S. Rocha,Oscar N. Mesquita +5 more
TL;DR: In this paper, a first-principles theory of trapping forces with no adjustable parameters, corrected for spherical aberration, is experimentally tested, and the authors find generally good agreement for the transverse trap stiffness as a function of microsphere radius for a broad range of radii.
Journal ArticleDOI
Transition on the entropic elasticity of DNA induced by intercalating molecules.
TL;DR: The results show that the persistence length of the DNA-drug complexes increases strongly as the drug concentration increases up to some critical value, and remains approximately constant for larger drug concentrations, at least in the concentration range used in the experiments.
Journal ArticleDOI
DNA-doxorubicin interaction: New insights and peculiarities.
TL;DR: Analysis of the interaction of the DNA molecule with the anticancer drug doxorubicin (doxo) by using three different experimental techniques has proven that the physical chemistry of such interaction can be modulated by changing the ionic strength of the surrounding buffer.
Journal ArticleDOI
Extracting physical chemistry from mechanics: a new approach to investigate DNA interactions with drugs and proteins in single molecule experiments
TL;DR: A historical survey of the attempts to connect mechanics to physical chemistry for DNA-ligand systems is presented, emphasizing a recently developed fitting approach useful to connect the persistence length of DNA- ligand complexes to the physicochemical properties of the interaction.