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Marco Coppi

Researcher at University of Florence

Publications -  33
Citations -  438

Marco Coppi is an academic researcher from University of Florence. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 15 publications receiving 143 citations.

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Ceftazidime-Avibactam Resistance Associated with Increased bla KPC-3 Gene Copy Number Mediated by pKpQIL Plasmid Derivatives in Sequence Type 258 Klebsiella pneumoniae .

TL;DR: The present findings provide novel insights about the mechanisms of acquired resistance to CZA, underscoring the role that the evolution of broadly disseminated pKpQIL plasmid derivatives may have in increasing the blaKPC gene copy number and KPC-3 expression in bacterial hosts.
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A simple phenotypic method for screening of MCR-1-mediated colistin resistance.

TL;DR: The colistin-MAC test could be a simple phenotypic test for presumptive identification of mcr-1-positive strains among isolates of colist in-resistant E. coli, based on a ≥8-fold reduction of colistsin MIC in the presence of DPA.
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Discrepancies in fosfomycin susceptibility testing of KPC-producing Klebsiella pneumoniae with various commercial methods.

TL;DR: Fosfomycin susceptibility testing with Sensititre, Vitek2, Etest, Mic Strip Test and disk diffusion methodologies was compared versus reference agar dilution method (AD), revealing a very low concordance with AD.
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SARS-CoV-2 Spike-Specific CD4+ T Cell Response Is Conserved Against Variants of Concern, Including Omicron

TL;DR: It is found that the ancestral (Wuhan strain) Spike protein can efficaciously reactivate CD4+ T cell memory in subjects with previous Alpha variant infection, providing an efficacious line of defense that can protect from the development of severe forms of COVID-19.