Francesco Annunziato

TL;DR: The demonstration of selective markers for human Th17 cells may help to understand their pathogenic role, and the identification of a subset of cells sharing features of both Th1 and Th17 may raise new issues concerning developmental and/or functional relationships between Th17 and Th1.

TL;DR: Results indicate that P can favor the development of Th cells producing Th2-type cytokines and is an inducer of both transient IL-4 production and CD30 expression in established Th1 cells.

TL;DR: It is shown that all IL-17–producing cells originate from CD161+ naive CD4+ T cells of umbilical cord blood, as well as of the postnatal thymus, in response to the combined activity of IL-1β and IL-23.

TL;DR: These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community providing the theory and key practical aspects offlow cytometry enabling immunologists to avoid the common errors that often undermine immunological data.

TL;DR: A novel chemokine-dependent reciprocal cross-talk between neutrophils and Th17 cells is revealed, which may represent a useful target for the treatment of chronic inflammatory diseases.