M
Marco Fumagalli
Researcher at University of Milan
Publications - 27
Citations - 635
Marco Fumagalli is an academic researcher from University of Milan. The author has contributed to research in topics: HaCaT & Proinflammatory cytokine. The author has an hindex of 11, co-authored 27 publications receiving 381 citations.
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Journal ArticleDOI
HaCaT Cells as a Reliable In Vitro Differentiation Model to Dissect the Inflammatory/Repair Response of Human Keratinocytes
Irma Colombo,Enrico Sangiovanni,Roberta Maggio,Carlo Mattozzi,Stefania Zava,Yolanda Corbett,Marco Fumagalli,Claudia Carlino,Paola Antonia Corsetto,Diletta Scaccabarozzi,Stefano Calvieri,Angela Gismondi,Donatella Taramelli,Mario Dell'Agli +13 more
TL;DR: HaCaT cells, a long-lived, spontaneously immortalized human keratinocyte line which is able to differentiate in vitro, is investigated as a suitable model to follow the release of inflammatory and repair mediators in response to TNFα or IL-1β to highlight that Ca2+ concentration in the medium, cell density, and presence of serum influences at different levels therelease of proinflammatory mediators by HaCaT Cells.
Journal ArticleDOI
Cannabis sativa L. extract and cannabidiol inhibit in vitro mediators of skin inflammation and wound injury
Enrico Sangiovanni,Marco Fumagalli,B Pacchetti,Stefano Piazza,Andrea Magnavacca,Saba Khalilpour,Gloria Melzi,Giulia Martinelli,Mario Dell'Agli +8 more
TL;DR: The findings provide new insights into the potential effect of Cannabis extracts against inflammation‐based skin diseases and down‐regulation of genes involved in wound healing and skin inflammation was at least in part due to the presence of cannabidiol.
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Phenolic profiles and anti-inflammatory activities of sixteen table grape (Vitis vinifera L.) varieties.
Francesca Colombo,Chiara Di Lorenzo,Luca Regazzoni,Marco Fumagalli,Enrico Sangiovanni,Luis Peres de Sousa,Luigi Bavaresco,Diego Tomasi,Antonella Bosso,Giancarlo Aldini,Patrizia Restani,Mario Dell'Agli +11 more
TL;DR: In this paper, two methods were developed to characterize sixteen varieties of table and wine grapes: (1) a LC-MS method to identify major and minor phenolic compounds; and (2) a HPLC-DAD method to quantify the most representative compounds.
Journal ArticleDOI
The effect of in vitro gastrointestinal digestion on the anti-inflammatory activity of Vitis vinifera L. leaves
Enrico Sangiovanni,C. Di Lorenzo,Elisa Colombo,Francesca Colombo,Marco Fumagalli,Gianfranco Frigerio,Patrizia Restani,Mario Dell'Agli +7 more
TL;DR: The findings suggest that PFS containing water extracts from Vitis vinifera L. leaves could be useful to inhibit/attenuate gastric inflammation inhibiting IL-8 secretion and expression through impairment of the NF-κB pathway.
Journal ArticleDOI
Strawberry tannins inhibit IL-8 secretion in a cell model of gastric inflammation
Marco Fumagalli,Enrico Sangiovanni,Urska Vrhovsek,Stefano Piazza,Elisa Colombo,Mattia Gasperotti,Fulvio Mattivi,Emma De Fabiani,Mario Dell'Agli +8 more
TL;DR: It is concluded that strawberry tannins, even after in vitro simulated gastric digestion, exert anti-inflammatory activities at nutritionally relevant concentrations.