Marcus Davis Machado Braga

TL;DR: The kala-azar control program, adopted by the Fundacao Nacional de Saude- FNS (National Health Foundation) has not been able to reduce to an acceptable level the incidence of human cases and the low sensitivity of the test used and the continuing residence of the infected dog in the region may be critical in the lack of success of this program.

TL;DR: The slowness of blood flow and of glomerular filTration resulted in more time for filtration and tubular reabsorption, with elevation of the total percentage of sodium and chlorine re absorption, and the necrosis observed was the result of damage cell induced by l-amino acid oxidase isolated from B. insularis venom.

TL;DR: An autopsied case is reported concerning fulminant sepsis with predominantly pulmonary lesions, caused by Burkholderia pseudomallei, etiologic agent of melioidosis, originating from interior of Ceará State, Northeastern Brazil where there had been no previous cases reported.

TL;DR: It is postulate that the C-type lectin B. insularis promoted its effects probably through interactions with endothelial cells or through the release of other mediators by tubular, mesangial and endothelium cells, as demonstrated by the rise in permeability of glomerular endothelial Cells.

TL;DR: Bothrops insularis venom promoted renal alterations in the isolated perfused rat kidney and the chromatographic profile showed 7 main fractions and the main phospholipase A(2) (PLA(2)) enzymatic activity was detected in fractions IV and V.