M
Margaret E. Brosnan
Researcher at Memorial University of Newfoundland
Publications - 111
Citations - 7138
Margaret E. Brosnan is an academic researcher from Memorial University of Newfoundland. The author has contributed to research in topics: Homocysteine & Creatine. The author has an hindex of 44, co-authored 111 publications receiving 6233 citations.
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The Sulfur-Containing Amino Acids: An Overview
TL;DR: Cysteine, by virtue of its ability to form disulfide bonds, plays a crucial role in protein structure and in protein-folding pathways, and may be converted to such important products as glutathione and taurine.
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Branched-Chain Amino Acids: Enzyme and Substrate Regulation
TL;DR: The fact that the flux-generating step for the catabolism of the three BCAAs occurs at one of the common steps indicates that the production of these downstream products are not individually regulated and, hence, may not play important individual roles.
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Creatine: endogenous metabolite, dietary, and therapeutic supplement.
TL;DR: It is evident that creatine plays a critical, though underappreciated, role in brain function.
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Is it time to reevaluate methyl balance in humans
TL;DR: It is suggested that creatine synthesis is responsible for a smaller proportion of AdoMet-derived methyl groups than has been suggested and that phosphatidylcholine synthesis via phosphatidethanolamine methyltransferase is a major consumer of these methyl groups.
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Renal arginine synthesis: studies in vitro and in vivo.
TL;DR: The results suggest that the availability of citrulline is a limiting factor for renal arginine synthesis in rats.