Margaret J. Velardo

TL;DR: The tropism and transduction frequency in the central nervous system of three different rAAV vector serotypes are investigated, suggesting that vectors based on distinct AAV serotypes can be chosen for specific applications in the nervous system.

TL;DR: The molecular and anatomical observations have identified a novel, longitudinal perspective of the post-SCI response, namely, that of a highly orchestrated tissue repair and remodeling repertoire with a prominent cutaneous wound healing signature that is conserved between two widely differing rat strains.

TL;DR: In this article, a method of treating neurodegenerative conditions is provided, which can include isolating neural stem cells from regions where specific types of neurons corresponding to the neurons to be replaced are generated.

TL;DR: This chapter discusses the concept of gray matter repair in the cervical spinal cord and describes the findings involving grafts of the neuronal precursor rich Ntera2 human cell line in chronic contusion lesions of the midcervical spinal cord.

TL;DR: The present chapter explores principles underlying neural-tissue reactions to trauma and how these differ relative to peripheral nervous system (PNS) vs central nervous System (CNS) pathologies and potential therapeutic interventions designed to rescue tissue at risk or promote regeneration and neuronal replacement.