Margarida Saramago

TL;DR: In bacteria, RNases act as a global regulatory network extremely important for the regulation of RNA levels, and intervene in the decay of many different mRNAs and small noncoding RNAs.

TL;DR: This review gives many illustrative examples of the role of RNases in the regulation of small RNAs, and it is very important to further understand their role in the post-transcriptional control of gene expression.

TL;DR: Evidence is reported showing that around one-third of the mapped mRNAs of the major human pathogen Staphylococcus aureus carry 3′-UTRs longer than 100-nt and thus, potential regulatory functions, which provide a singular example of a new potential post-transcriptional regulatory mechanism to modulate bacterial gene expression through the interaction of a 3-UTR with the 5-utR of the same mRNA.

TL;DR: The main conclusion of this work is the existence of two independent pathways for MicA turnover, each pathway involves a distinct endoribonuclease, having a different role in the context of the fine-tuned regulation of porin levels.

TL;DR: RNAs are important effectors in the process of gene expression and constant adaptation to environmental demands is accompanied by a continual adjustment of transcripts' levels, which conditions the pathways and mechanisms of RNA degradation.