M
Margaux Sambon
Researcher at University of Liège
Publications - 8
Citations - 119
Margaux Sambon is an academic researcher from University of Liège. The author has contributed to research in topics: Thiamine & Benfotiamine. The author has an hindex of 4, co-authored 6 publications receiving 67 citations.
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Journal ArticleDOI
Thiamine and benfotiamine prevent stress-induced suppression of hippocampal neurogenesis in mice exposed to predation without affecting brain thiamine diphosphate levels.
Julie Vignisse,Margaux Sambon,Anna Gorlova,D. A. Pavlov,Nicolas Caron,Brigitte Malgrange,Elena F. Shevtsova,Andrey A. Svistunov,Daniel C. Anthony,Natalyia Markova,Natalyia Bazhenova,Bernard Coumans,Bernard Lakaye,Pierre Wins,Tatyana Strekalova,Tatyana Strekalova,Lucien Bettendorff +16 more
TL;DR: It is demonstrated, for the first time, that thiamine and benfotiamine prevent stress‐induced inhibition of hippocampal neurogenesis and accompanying physiological changes, and might be useful as a complementary therapy in several neuropsychiatric disorders.
Journal ArticleDOI
Thiamine and benfotiamine counteract ultrasound-induced aggression, normalize AMPA receptor expression and plasticity markers, and reduce oxidative stress in mice
Anna Gorlova,D. A. Pavlov,Daniel C. Anthony,Eugene D. Ponomarev,Margaux Sambon,Andrey Proshin,Igor Shafarevich,Diana Babaevskaya,Klaus-Peter Lesсh,Lucien Bettendorff,Tatyana Strekalova,Tatyana Strekalova +11 more
TL;DR: Thiamine compounds were able to counteract ultrasound- induced aggression, which was accompanied by the normalization of markers that have been showed to be associated with ultrasound-induced aggression.
Journal ArticleDOI
Thiamine and benfotiamine protect neuroblastoma cells against paraquat and β-amyloid toxicity by a coenzyme-independent mechanism.
Margaux Sambon,Aurore Napp,Alice Demelenne,Julie Vignisse,Pierre Wins,Marianne Fillet,Lucien Bettendorff +6 more
TL;DR: Benfotiamine (BFT) is a synthetic thiamine precursor with high bioavailability and it is efficient in treating complications of type 2 diabetes and has beneficial effects in mouse models of neurodegenerative diseases.
Journal ArticleDOI
Dibenzoylthiamine Has Powerful Antioxidant and Anti-Inflammatory Properties in Cultured Cells and in Mouse Models of Stress and Neurodegeneration.
Margaux Sambon,Anna Gorlova,Anna Gorlova,Alice Demelenne,Judit Alhama-Riba,Judit Alhama-Riba,Bernard Coumans,Bernard Lakaye,Pierre Wins,Marianne Fillet,Daniel C. Anthony,Daniel C. Anthony,Tatyana Strekalova,Tatyana Strekalova,Lucien Bettendorff +14 more
TL;DR: The data suggest that DBT may have therapeutic potential for brain pathology associated with oxidative stress and inflammation by novel, coenzyme-independent mechanisms.
Journal ArticleDOI
Neuroprotective Effects of Thiamine and Precursors with Higher Bioavailability: Focus on Benfotiamine and Dibenzoylthiamine.
TL;DR: In this paper, the identification of the active neuroprotective derivatives and the clarification of their mechanism of action open extremely promising perspectives in the field of neurodegenerative, neurodevelopmental and psychiatric conditions.