M
Maria Auxiliadora Coelho Kaplan
Researcher at Federal University of Rio de Janeiro
Publications - 202
Citations - 4256
Maria Auxiliadora Coelho Kaplan is an academic researcher from Federal University of Rio de Janeiro. The author has contributed to research in topics: Essential oil & Piperaceae. The author has an hindex of 31, co-authored 200 publications receiving 3887 citations. Previous affiliations of Maria Auxiliadora Coelho Kaplan include University of São Paulo & Bar-Ilan University.
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Journal ArticleDOI
Natural triterpenoids from Cecropia lyratiloba are cytotoxic to both sensitive and multidrug resistant leukemia cell lines
Gleice da Graça Rocha,Marisol Simões,Kelly Araujo Lucio,Rodrigo Rodrigues de Oliveira,Maria Auxiliadora Coelho Kaplan,Cerli Rocha Gattass +5 more
TL;DR: The cytotoxicity of four triterpenoids isolated from the roots of Cecropia lyratiloba was evaluated in vitro in sensitive and multidrug resistant leukemia cell lines, revealing the potential of the terpenoids as source for the development of new anti-neoplastic and anti-MDR drugs.
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Improvement of In Vitro and In Vivo Antileishmanial Activities of 2′,6′-Dihydroxy-4′-Methoxychalcone by Entrapment in Poly(d,l-Lactide) Nanoparticles
Eduardo Caio Torres-Santos,Jose Maciel Rodrigues,Davyson de Lima Moreira,Maria Auxiliadora Coelho Kaplan,Bartira Rossi-Bergmann +4 more
TL;DR: The inhibition of intracellular Leishmania amazonensis growth by 2′,6′-dihydroxy-4′-methoxychalcone (DMC) isolated from Piper aduncum was further enhanced after encapsulated DMC in polymeric nanoparticles.
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Potential cytotoxic activity of some Brazilian seaweeds on human melanoma cells
Fabíola D. Rocha,Angélica Ribeiro Soares,Peter J. Houghton,Renato Crespo Pereira,Maria Auxiliadora Coelho Kaplan,Valéria Laneuville Teixeira +5 more
TL;DR: In vitro screening of the crude extracts of some Brazilian coastal seaweeds for cytotoxic activity against a cultured human melanoma cancer cell line using the sulphorhodamine B assay was performed and the crude dichloromethane:chloroform extract of Stypopodium zonale showed good cytotoxicity activity against the C32 cell line.
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Topical antiinflammatory and analgesic activities of Copaifera duckei dwyer
José Carlos Tavares Carvalho,V. Cascon,L. S. Possebon,M. S. S. Morimoto,L.G.V. Cardoso,Maria Auxiliadora Coelho Kaplan,B. Gilbert +6 more
TL;DR: Results suggest that the Copaifera duckei oleoresin has topical antiinflammatory and analgesic activities, similar to that observed with dexamethasone.
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Antimicrobial activity of benzylisoquinoline alkaloids from Annona salzmanii D.C.
Marçal de Queiroz Paulo,JoséM. Barbosa-Filho,Edeltrudes de Oliveira Lima,Ricardo Fernandes Maia,Rita de Cassia,B.B.C. Barbosa,Maria Auxiliadora Coelho Kaplan +6 more
TL;DR: Bark of Annona salzmanii D.C. (Annonaceae), used in Brazilian folk medicine, was found to contain four benzylisoquinoline alkaloids, namely reticuline, anonaine, laurelliptine and isoboldine, which show some antifungal activity.