M
Maria Cristina Roque-Barreira
Researcher at University of São Paulo
Publications - 155
Citations - 3876
Maria Cristina Roque-Barreira is an academic researcher from University of São Paulo. The author has contributed to research in topics: Paracoccidioides brasiliensis & Immune system. The author has an hindex of 34, co-authored 150 publications receiving 3503 citations. Previous affiliations of Maria Cristina Roque-Barreira include Necker-Enfants Malades Hospital.
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Journal Article
Jacalin: an IgA-binding lectin.
TL;DR: It is demonstrated that IgA is probably the major serum constituent precipitated by the lectin and that no IgG or IgM can be detected in the precipitates and on the basis of this specificity a simple and reliable affinity chromatography procedure is described for the purification of both human serum and colostrum IgA.
Journal ArticleDOI
Charge and size of mesangial IgA in IgA nephropathy.
Renato C. Monteiro,Lise Halbwachs-Mecarelli,Maria Cristina Roque-Barreira,Laure-Hélène Noël,Jean Berger,Philippe Lesavre +5 more
TL;DR: It is shown that the multimeric nature of IgA, the formation of IgC complexes, and the anionic charge of Ig a are likely to be involved in the mesangial IgA deposition in idiopathic IgA nephropathy.
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Toxoplasma gondii Infection Reveals a Novel Regulatory Role for Galectin-3 in the Interface of Innate and Adaptive Immunity
Emerson Soares Bernardes,Neide M. Silva,Luciana Pereira Ruas,José Roberto Mineo,Adriano Motta Loyola,Daniel K. Hsu,Fu-Tong Liu,Roger Chammas,Maria Cristina Roque-Barreira +8 more
TL;DR: It is concluded that galectin-3 exerts an important role in innate immunity, including not only a pro-inflammatory effect but also a regulatory role on dendritic cells, capable of interfering in the adaptive immune response.
Journal ArticleDOI
The immunomodulatory effect of plant lectins: a review with emphasis on ArtinM properties
Maria Aparecida de Souza,Fernanda C. Carvalho,Luciana Pereira Ruas,Rafael Ricci-Azevedo,Maria Cristina Roque-Barreira +4 more
TL;DR: A comprehensive review of the effects that some plant lectins exert as immunomodulatory agents, showing that they are able to positively modify the immune response to certain pathological conditions, such as cancer and infections is presented.
Journal Article
A neutrophil migration-inducing lectin from Artocarpus integrifolia.
R. Santos-De-Oliveira,Marcelo Dias-Baruffi,Sandra Maria de Oliveira Thomaz,Leila Maria Beltramini,Maria Cristina Roque-Barreira +4 more
TL;DR: The physical and biologic properties of KM+ suggest that this lectin may attract neutrophils by a mechanism involving a haptotactic gradient as has been proposed for IL-8 and might be used as tool to study protein-carbohydrate interactions during neutrophil migration through the extracellular matrix.