Maria Domenica Cappellini

TL;DR: Iron overload was observed between patients who underwent splenectomy and non-splenectomized patients, and the levels of transferrin saturation, serum ferritin and desferrioxamine-induced urinary iron excretion were significantly higher in splenECTomized than in non- splenected patients, indicating that the spleen could have a role in the regulation of iron metabolism in these patients.

TL;DR: A high prevalence of anemia in elderly patients, and its association with a higher number of comorbidities and a longer stay is confirmed, confirming its negative impact on patients' quality of life and its social burden in term of healthcare needs and costs.

TL;DR: Non-transferrin-bound iron could have a role in initiating or promoting alcohol-induced liver damage and may be associated independently with alcohol intake and total bilirubin.

TL;DR: Using data from screened patients and those treated with deferasirox for up to 2 years, clinically relevant serum ferritin thresholds for the initiation of chelation therapy are identified, as well as thresholds to guide chelator dose interruption and dose escalation.

TL;DR: Italian patients with porphyria cutanea tarda and iron overload appear to have one or even two genes for genetic hemochromatosis.