M
Maria Domenica Cappellini
Researcher at University of Milan
Publications - 570
Citations - 21441
Maria Domenica Cappellini is an academic researcher from University of Milan. The author has contributed to research in topics: Thalassemia & Deferasirox. The author has an hindex of 71, co-authored 518 publications receiving 18668 citations. Previous affiliations of Maria Domenica Cappellini include Centra & Vita-Salute San Raffaele University.
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Journal ArticleDOI
High nontransferrin bound iron levels and heart disease in thalassemia major.
Antonio Piga,Filomena Longo,Lorena Duca,Simona Roggero,T. Vinciguerra,Roberto Calabrese,Chaim Hershko,Maria Domenica Cappellini +7 more
TL;DR: This is the first documentation of a link between the presence of NTBI in thalassemic patients with transfusional iron overload and heart disease, and whether NTBI assessment may have a role in evaluating the risks and optimizing treatment for transfusion‐dependent patients.
Journal ArticleDOI
Prospective evaluation of patient-reported outcomes during treatment with deferasirox or deferoxamine for iron overload in patients with beta-thalassemia
Maria Domenica Cappellini,Mohamed Bejaoui,Leyla Agaoglu,John B. Porter,Thomas D. Coates,Michael Jeng,Maria Eliana Lai,Antonio Mangiagli,Gabriele Strauss,Robert Girot,Nora Watman,Alina Ferster,Sandra Loggetto,Sharon Abish,Holger Cario,Nicolaos Zoumbos,Elliott Vichinsky,Herbert Opitz,C. Ressayre-Djaffer,Linda Abetz,Diana Rofail,Jean Francois Baladi +21 more
TL;DR: The results suggest that deferasirox had a positive impact on patients' daily lives, and patient-reported satisfaction and convenience were significantly higher for the once-daily, oral ICT defer asirox than for DFO infusions.
Journal ArticleDOI
Oxidative status and malondialdehyde in β-thalassaemia patients
Giuliana Cighetti,Lorena Duca,Luana Bortone,S. Sala,Isabella Nava,Gemino Fiorelli,Maria Domenica Cappellini +6 more
TL;DR: The aim of this study was to detect and correlate iron overload parameters with the oxidative stress and the antioxidant capability in β‐thalassaemia patients.
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A reappraisal of Gaucher disease-diagnosis and disease management algorithms.
Pramod K. Mistry,Maria Domenica Cappellini,Elena Lukina,Hayri Özsan,Sara Mach Pascual,Hanna Rosenbaum,María Helena Solano,Zachary Spigelman,Jesús Villarrubia,Nora Watman,Gero Massenkeil +10 more
TL;DR: To help promote timely diagnosis and optimal management of the protean presentations of Gaucher disease, a consensus meeting was convened to develop algorithms for diagnosis and disease management for Gauchers disease.
Journal ArticleDOI
Deferasirox reduces iron overload significantly in nontransfusion-dependent thalassemia: 1-year results from a prospective, randomized, double-blind, placebo-controlled study
Ali T. Taher,John B. Porter,Vip Viprakasit,Antonis Kattamis,Suporn Chuncharunee,Pranee Sutcharitchan,Noppadol Siritanaratkul,Renzo Galanello,Zeynep Karakas,Tomasz Lawniczek,Jacqueline Ros,Yiyun Zhang,Dany Habr,Maria Domenica Cappellini +13 more
TL;DR: This is the first randomized study showing that iron chelation with deferasirox significantly reduces iron overload in NTDT patients with a frequency of overall adverse events similar to placebo.