M
María Esperanza Ruiz
Researcher at National University of La Plata
Publications - 32
Citations - 860
María Esperanza Ruiz is an academic researcher from National University of La Plata. The author has contributed to research in topics: Solid lipid nanoparticle & Drug delivery. The author has an hindex of 9, co-authored 29 publications receiving 476 citations. Previous affiliations of María Esperanza Ruiz include National Scientific and Technical Research Council.
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Risks of Self-Medication Practices
TL;DR: In this short review the author analyzes recent literature on some of the most important dangers related to self-medication practices, particularly: polypharmacy and drug interactions, medications abuse or dependence, misdiagnosis and incorrect choice of treatment.
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Solid Lipid Nanoparticles for Drug Delivery: Pharmacological and Biopharmaceutical Aspects
TL;DR: The currently active clinical trials on lipid nanoparticles were reviewed, with a brief discussion on what achievements or milestones are still to be reached, as a way of understanding the reasons for the scarce number of solid lipid nanoparticle undergoing clinical trials.
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Carbamazepine-loaded solid lipid nanoparticles and nanostructured lipid carriers: Physicochemical characterization and in vitro/in vivo evaluation.
Sebastián Scioli Montoto,María Laura Sbaraglini,Alan Talevi,Manuel Couyoupetrou,M. Di Ianni,Guido Pesce,Vera Alejandra Alvarez,Luis E. Bruno-Blanch,Guillermo R. Castro,María Esperanza Ruiz,German Abel Islan +10 more
TL;DR: The developed CBZ-loaded lipid nanocarriers displayed optimal characteristics of size, shape and drug release and possibly represent a promising tool to improve the treatment of refractory epilepsy linked to efflux transporters upregulation.
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Hybrid Ofloxacin/eugenol co-loaded solid lipid nanoparticles with enhanced and targetable antimicrobial properties
Boris Rodenak-Kladniew,Sebastián Scioli Montoto,María Laura Sbaraglini,M. Di Ianni,María Esperanza Ruiz,Alan Talevi,Vera Alejandra Alvarez,Nelson Durán,Guillermo R. Castro,German Abel Islan +9 more
TL;DR: It was proved that the administration of hybrid SLN to mice by dry powder inhalation reached therapeutic Ofx levels in lungs and the SLN exhibited an enhanced bactericidal activity against Pseudomonas aeruginosa and Staphylococcus aureus.
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Applications of nanosystems to anticancer drug therapy (Part II. Dendrimers, micelles, lipid-based nanosystems).
TL;DR: Analysis of recent patents on linear polymer-based nanosystems (nanogels, nanospheres and nanocapsules) applications to cancer therapy is expanded to branched polymers (dendrimers), self-assembling nanomicelles and lipid- based nanocarriers.