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Maria Grazia Ammendolia

Researcher at Istituto Superiore di Sanità

Publications -  68
Citations -  2403

Maria Grazia Ammendolia is an academic researcher from Istituto Superiore di Sanità. The author has contributed to research in topics: Lactoferrin & Virus. The author has an hindex of 27, co-authored 63 publications receiving 2075 citations. Previous affiliations of Maria Grazia Ammendolia include University of Messina & Sapienza University of Rome.

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Antirotaviral activity of milk proteins: lactoferrin prevents rotavirus infection in the enterocyte-like cell line HT-29.

TL;DR: It was shown that apo-lactoferrin hinders virus attachment to cell receptors since it is able to bind the viral particles and to prevent both rotavirus haemagglutination and viral binding to susceptible cells.
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Enterococcus spp. produces slime and survives in rat peritoneal macrophages

TL;DR: Enterococcal clinical isolates were investigated for the ability to form biofilm on inert surfaces, as a measure of slime production, in an attempt to find new possible virulence factors for these microorganisms to indicate a role of slime for survival in stressful conditions.
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Slime Production and Expression of the Slime-Associated Antigen by Staphylococcal Clinical Isolates

TL;DR: expression of the slime-associated antigen appeared to be species specific and confined to the Staphylococcus epidermidissensu stricto isolates, and its strong association with the ability of these strains to produce thicker biofilms indicated slime- associated antigen as a possible virulence marker for S. epidersmidis.
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Inhibition of poliovirus type 1 infection by iron-, manganese- and zinc-saturated lactoferrin.

TL;DR: Zinc lactoferrin was the sole compound capable of inhibiting a phase of infection subsequent to virus internalization into the host cells, as well as preventing viral replication when present during the entire cycle of poliovirus infection or during the viral adsorption step.
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Iron availability influences aggregation, biofilm, adhesion and invasion of Pseudomonas aeruginosa and Burkholderia cenocepacia.

TL;DR: The data reported in this study indicate that low iron concentration induced free-living forms and motility both in P. aeruginosa and B. cenocepacia, while high iron concentrations stimulated aggregation and biofilm formation already in the fluid phases, so demonstrating that aggregation andBiofilm formation are positively iron-modulated in these bacteria.