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Andrea Battistoni

Researcher at University of Rome Tor Vergata

Publications -  157
Citations -  5408

Andrea Battistoni is an academic researcher from University of Rome Tor Vergata. The author has contributed to research in topics: Superoxide dismutase & Active site. The author has an hindex of 40, co-authored 152 publications receiving 4939 citations. Previous affiliations of Andrea Battistoni include University of Pavia & Boston Children's Hospital.

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Expression of a Cu,Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis induces mitochondrial alteration and increase of cytosolic Ca2+ concentration in transfected neuroblastoma SH-SY5Y cells

TL;DR: It is reported that G93A induces a significant loss of mitochondrial membrane potential, an increased sensitivity toward valinomycin and a parallel increase in cytosolic Ca2+ concentration, which are not related to total Cu,ZnSOD content and activity in the cell.
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High-affinity Zn2+ uptake system ZnuABC is required for bacterial zinc homeostasis in intracellular environments and contributes to the virulence of Salmonella enterica

TL;DR: The amount of free metals available for bacterial growth within the infected animal is limited, despite the apparent elevated concentration of free metal within cells and in plasma, and it is suggested that Salmonella exploits the ZnuABC zinc transporter to maximize zinc availability in such conditions.
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Oxidative stress and antioxidant therapy in cystic fibrosis

TL;DR: All aspects examined in this critical review of the literature clearly suggest that further and more rigorous trials are needed together with new generations of pharmacological tools to a more effective antioxidant and anti-inflammatory therapy of cystic fibrosis patients.