M
María José Buitrago
Researcher at Carlos III Health Institute
Publications - 58
Citations - 2279
María José Buitrago is an academic researcher from Carlos III Health Institute. The author has contributed to research in topics: Histoplasmosis & Aspergillosis. The author has an hindex of 27, co-authored 55 publications receiving 2017 citations.
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Journal ArticleDOI
Head-to-Head Comparison of the Activities of Currently Available Antifungal Agents against 3,378 Spanish Clinical Isolates of Yeasts and Filamentous Fungi
Manuel Cuenca-Estrella,Alicia Gomez-Lopez,Emilia Mellado,María José Buitrago,Araceli Monzón,Juan L. Rodriguez-Tudela +5 more
TL;DR: Posaconazole and currently available antifungal agents exhibit a potent activity in vitro against the majority of pathogenic fungal species.
Journal ArticleDOI
Comparison of the Vitek 2 antifungal susceptibility system with the clinical and laboratory standards institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) Broth Microdilution Reference Methods and with the Sensititre YeastOne and Etest techniques for in vitro detection of antifungal resistance in yeast isolates.
Manuel Cuenca-Estrella,Alicia Gomez-Lopez,Ana Alastruey-Izquierdo,Leticia Bernal-Martinez,Isabel Cuesta,María José Buitrago,Juan L. Rodriguez-Tudela +6 more
TL;DR: In this article, the Vitek 2 system for antifungal susceptibility testing of yeast species was evaluated and compared with those obtained by the reference procedures of both the CLSI and the European Committee on Antimicrobial Susceptibility Testing (EUCAST).
Journal ArticleDOI
Targeted Gene Disruption of the 14-α Sterol Demethylase (cyp51A) in Aspergillus fumigatus and Its Role in Azole Drug Susceptibility
Emilia Mellado,Guillermo Garcia-Effron,María José Buitrago,Laura Alcazar-Fuoli,Manuel Cuenca-Estrella,Juan L. Rodriguez-Tudela +5 more
TL;DR: Targeted disruption of cyp51A in azole-susceptible and -resistant strains decreased MICs from 2- to 40-fold, and mutants were morphologically indistinguishable from the wild-type strain, retaining the ability to cause pulmonary disease in neutropenic mice.
Journal ArticleDOI
Value of Serial Quantification of Fungal DNA by a Real-Time PCR-Based Technique for Early Diagnosis of Invasive Aspergillosis in Patients with Febrile Neutropenia
Manuel Cuenca-Estrella,Yolanda Meije,Carmen Díaz-Pedroche,Alicia Gomez-Lopez,María José Buitrago,Leticia Bernal-Martinez,Carlos Grande,Rafael San Juan,Manuel Lizasoain,Juan L. Rodriguez-Tudela,Jose M. Aguado +10 more
TL;DR: The serial detection of Aspergillus DNA using real-time quantitative PCR has great diagnostic applicability, which increases when combined with GM quantification.
Journal ArticleDOI
Scopulariopsis brevicaulis, a Fungal Pathogen Resistant to Broad-Spectrum Antifungal Agents
Manuel Cuenca-Estrella,Alicia Gomez-Lopez,Emilia Mellado,María José Buitrago,Araceli Monzón,Juan L. Rodriguez-Tudela +5 more
TL;DR: Antifungal susceptibility results for 32 clinical isolates of Scopulariopsis brevicaulis are presented and MICs of amphotericin B, voriconazole, and terbinafine for all isolates were high.