M
Maria Luisa Sacchetti
Researcher at Sapienza University of Rome
Publications - 46
Citations - 2379
Maria Luisa Sacchetti is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Stroke & Cerebral infarction. The author has an hindex of 22, co-authored 46 publications receiving 2304 citations. Previous affiliations of Maria Luisa Sacchetti include NewYork–Presbyterian Hospital.
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Journal ArticleDOI
Clinical and instrumental evaluation of patients with ischemic stroke within the first six hours
Cesare Fieschi,Corrado Argentino,Gian Luigi Lenzi,Maria Luisa Sacchetti,Danilo Toni,Luigi Bozzao +5 more
TL;DR: The data indicate that early pathophysiological studies augment the clinical information and should be taken into account in the design and analysis of therapeutic trials of acute ischemic stroke.
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Progressing Neurological Deficit Secondary to Acute Ischemic Stroke: A Study on Predictability, Pathogenesis, and Prognosis
Danilo Toni,Marco Fiorelli,Mara Gentile,Stefano Bastianello,Maria Luisa Sacchetti,Corrado Argentino,Carlo Pozzilli,Cesare Fieschi +7 more
TL;DR: Early stroke deterioration is still an event that is difficult to predict; it is largely determined by cerebral edema following an arterial occlusion, as indicated by an early focal hypodensity and initial mass effect on the baseline CT scan.
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Hemorrhagic transformation of brain infarct: predictability in the first 5 hours from stroke onset and influence on clinical outcome.
Danilo Toni,Marco Fiorelli,Stefano Bastianello,Maria Luisa Sacchetti,Giuliano Sette,Corrado Argentino,E. Montinaro,Luigi Bozzao +7 more
TL;DR: HT of a brain infarct is a common event that occurs independently of anticoagulation and can be reliably predicted as early as 5 hours from stroke onset by the presence of focal hypodensity at CT.
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Circadian variation in the frequency of ischemic stroke.
Corrado Argentino,Danilo Toni,Maurizia Rasura,Francesco Violi,Maria Luisa Sacchetti,A Allegretta,Francesco Balsano,Cesare Fieschi +7 more
TL;DR: The frequency of myocardial infarction and sudden death is increased between 6 AM and noon, and the identification of periods of high risk for vascular events may have important therapeutic implications, such as matching drug effects with vulnerability.
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Prognostic significance of admission levels of troponin I in patients with acute ischaemic stroke
E Di Angelantonio,Marco Fiorelli,Danilo Toni,Maria Luisa Sacchetti,Svetlana Lorenzano,Anne Falcou,M V Ciarla,Suppa M,Luca Bonanni,Giuliano Bertazzoni,Aguglia F,Corrado Argentino +11 more
TL;DR: Cardiac troponin I positivity on admission is an independent prognostic predictor in acute ischaemic stroke and whether further evaluation and treatment of cTnI positive patients can reduce cardiac morbidity and mortality should be the focus of future research.