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Svetlana Lorenzano

Researcher at Sapienza University of Rome

Publications -  58
Citations -  1565

Svetlana Lorenzano is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Stroke & Thrombolysis. The author has an hindex of 16, co-authored 48 publications receiving 1297 citations. Previous affiliations of Svetlana Lorenzano include Yale University & Brown University.

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Hemorrhagic Transformation Within 36 Hours of a Cerebral Infarct Relationships With Early Clinical Deterioration and 3-Month Outcome in the European Cooperative Acute Stroke Study I (ECASS I) Cohort

TL;DR: In this article, the authors investigated the cohort of a randomized trial of thrombolysis to assess the early and late clinical course associated with different subtypes of hemorrhagic infarction (HI) and parenchymal hematoma (PH) detected within the first 36 hours of an ischemic stroke.
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Prognostic significance of admission levels of troponin I in patients with acute ischaemic stroke

TL;DR: Cardiac troponin I positivity on admission is an independent prognostic predictor in acute ischaemic stroke and whether further evaluation and treatment of cTnI positive patients can reduce cardiac morbidity and mortality should be the focus of future research.
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Does sex influence the response to intravenous thrombolysis in ischemic stroke?: answers from safe implementation of treatments in Stroke-International Stroke Thrombolysis Register

TL;DR: It is suggested that intravenous thrombolysis may modify the observed survival and recovery advantage for men expected in the natural course of an ischemic stroke, with a possible larger beneficial treatment effect in women when compared with men.
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Intravenous thrombolysis with rt-PA in acute ischemic stroke patients aged older than 80 years in Italy.

TL;DR: The data suggest that thrombolytic therapy should not be a priori denied for appropriately selected >80-year-old patients but randomized controlled clinical trials are necessary before definite recommendations can be given.
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Fluid-Attenuated Inversion Recovery Hyperintensity Correlates With Matrix Metalloproteinase-9 Level and Hemorrhagic Transformation in Acute Ischemic Stroke

TL;DR: FR correlates with both MMP-9 level and risk of hemorrhage and may predict hemorrhagic transformation, possibly as a reflection of altered blood–brain barrier integrity.