M
Maria Mifsud
Researcher at Scripps Research Institute
Publications - 3
Citations - 277
Maria Mifsud is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Enantioselective synthesis & Catalysis. The author has an hindex of 2, co-authored 3 publications receiving 265 citations.
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Journal ArticleDOI
3-Pyrrolidinecarboxylic acid for direct catalytic asymmetric anti-Mannich-type reactions of unmodified ketones.
TL;DR: The position of the carboxylic acid group on the pyrrolidine ring directs the stereoselection of the catalyzed reaction, providing either syn- or anti-Mannich products.
Journal ArticleDOI
Catalysis of 3-pyrrolidinecarboxylic acid and related pyrrolidine derivatives in enantioselective anti-Mannich-type reactions: importance of the 3-acid group on pyrrolidine for stereocontrol.
Haile Zhang,Susumu Mitsumori,Naoto Utsumi,Masanori Imai,Noemi Garcia-Delgado,Maria Mifsud,Klaus Albertshofer,Paul Ha-Yeon Cheong,Kendall N. Houk,Fujie Tanaka,Carlos F. Barbas +10 more
TL;DR: Evaluation of a series of pyrrolidine-based catalysts indicated that the acid group at the beta-position of the p Pyrrolidine ring of the catalyst played an important role in forwarding the carbon-carbon bond formation and in directing anti-selectivity and enantioselectivity.