M
Maria Rosaria Romano
Researcher at University of Pisa
Publications - 21
Citations - 276
Maria Rosaria Romano is an academic researcher from University of Pisa. The author has contributed to research in topics: Glycal & Aziridine. The author has an hindex of 10, co-authored 21 publications receiving 261 citations.
Papers
More filters
Journal ArticleDOI
Stereospecific uncatalyzed α-O-glycosylation and α-C-glycosidation by means of a new D-gulal-derived α vinyl oxirane
TL;DR: The reaction of α vinyl oxirane 5, prepared through a new route to the d-gulal system, with O-nucleophiles (alcohols and di-O-isopropylidene-α-d-monosaccharides) and Cn-alkyls (lithium alkyls) affords, in a completely stereoselective way, the corresponding 2-unsaturated α O- and C-glycosides having the same configuration as the starting epoxide as mentioned in this paper.
Journal ArticleDOI
Regio- and Stereoselectivity of the Addition of O-, S-, N-, and C-Nucleophiles to the β Vinyl Oxirane Derived from d-Glucal
TL;DR: 6-O-Trityl- and 6-(O-benzyl)-substituted epoxide derived from D-glucal were examined in their addition reactions with O, C, N, and S-nucleophiles and a 1,2-syn-addition pathway was observed.
Journal ArticleDOI
Stereoselective synthesis of 4-(N-mesylamino)-2,3-unsaturated- alpha-O-glycosides via a new glycal-derived vinyl alpha-N-(mesyl)-aziridine.
TL;DR: N-Mesyl aziridine 7alpha is synthesized by cyclization of trans-N,O-dimesylate 6 with t-BuOK in anhydrous benzene by a completely regioselective 1,4-addition process that proceeds with high or complete alpha-stereoselectivity.
Journal ArticleDOI
Stereoselective Synthesis of 2,3-Unsaturated-aza-O-glycosides via New Diastereoisomeric N-Cbz-imino Glycal-Derived Allyl Epoxides†
Di Bussolo,Annalisa Fiasella,Maria Rosaria Romano,Lucilla Favero,Mauro Pineschi,Paolo Crotti +5 more
TL;DR: Diastereoisomeric D,L-N-Cbz-imino glycal-derived allyl epoxides 5 and 6 have been synthesized, and their addition reactions with alcohols examined, leading to a new, completely regioselective 1,4-addition process which proceeds with complete substrate-dependent stereoselectivity.
Journal ArticleDOI
Stereoselective uncatalyzed synthesis of 2,3-unsaturated-4-n-substituted-beta-O-glycosides by means of a new D-galactal-derived N-(mesyl)-aziridine.
TL;DR: The reaction of the new D-galactal-derived allylic aziridine 1beta with O-nucleophiles (alcohols and monosaccharides) affords, in a high to complete beta-stereoselectivity, the corresponding 2,3-unsaturated-beta-O-glycosides bearing a beta-N-functionality at C4.