M
Maria Vittoria Barone
Researcher at Stazione Zoologica Anton Dohrn
Publications - 4
Citations - 770
Maria Vittoria Barone is an academic researcher from Stazione Zoologica Anton Dohrn. The author has contributed to research in topics: Proto-oncogene tyrosine-protein kinase Src & SH3 domain. The author has an hindex of 2, co-authored 4 publications receiving 726 citations.
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Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation
Antimo Migliaccio,Gabriella Castoria,Marina Di Domenico,Antonietta de Falco,Antonio Bilancio,Maria Lombardi,Maria Vittoria Barone,Donatella Ametrano,Mariastella Zannini,Ciro Abbondanza,Ferdinando Auricchio +10 more
TL;DR: Hormone‐stimulated Src interaction with the androgen receptor and oestradiol receptor α or β is detected using glutathione S‐transferase fusion constructs and the role of this phosphotyrosine is stressed by its requirement for association of oestrogens receptor α with Src and consequent activation of Src in intact Cos cells.
Journal ArticleDOI
Inhibition of the SH3 domain-mediated binding of Src to the androgen receptor and its effect on tumor growth
Anna Rita Migliaccio,Lilian Varricchio,A. de Falco,Gabriella Castoria,Claudio Arra,Hiroshi Yamaguchi,Alessandra Ciociola,Maria Lombardi,R Di Stasio,Antonio Barbieri,Alfonso Baldi,Maria Vittoria Barone,Ettore Appella,Ferdinando Auricchio +13 more
TL;DR: The peptide is the first example of a specific inhibitor of steroid receptor-dependent signal transducing activity and the finding that the peptide strongly inhibits the growth of LNCaP xenografts established in nude mice is highlighted.