M
Marialuisa Bocchino
Researcher at University of Naples Federico II
Publications - 110
Citations - 1994
Marialuisa Bocchino is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Idiopathic pulmonary fibrosis & Tuberculosis. The author has an hindex of 21, co-authored 95 publications receiving 1674 citations. Previous affiliations of Marialuisa Bocchino include Seconda Università degli Studi di Napoli & University of Rome Tor Vergata.
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Journal ArticleDOI
Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection
Nadia Caccamo,Giuliana Guggino,Simone A. Joosten,Giuseppe Gelsomino,Paola Di Carlo,Lucina Titone,Domenico Galati,Marialuisa Bocchino,Alessandro Matarese,Alfredo Salerno,Alessandro Sanduzzi,Willeke P. J. Franken,Tom H. M. Ottenhoff,Francesco Dieli +13 more
TL;DR: The results suggest that phenotypic and functional signatures of CD4+ T cells may serve as immunological correlates of protection and curative host responses, and be a useful tool to monitor the efficacy of anti‐mycobacterial therapy.
Journal ArticleDOI
Apoptosis of human monocytes/macrophages in Mycobacterium tuberculosis infection.
Roberta Placido,Giorgio Mancino,Alessandra Amendola,Francesca Mariani,Silvia Vendetti,Mauro Piacentini,Alessandro Sanduzzi,Marialuisa Bocchino,Marek Zembala,Vittorio Colizzi +9 more
TL;DR: The capacity of MTB to induce apoptosis in cells obtained by broncho‐alveolar lavage from patients with reactive pulmonary tuberculosis and from AIDS patients with disseminated pulmonary tuberculosis is analyzed.
Journal ArticleDOI
Performance of two commercial blood IFN-γ release assays for the detection of Mycobacterium tuberculosis infection in patient candidates for anti-TNF-α treatment
Marialuisa Bocchino,Alessandro Matarese,Barbara Bellofiore,P. Giacomelli,G. Santoro,Nicola Balato,Fabiana Castiglione,Raffaele Scarpa,Francesco Perna,Giuseppe Signoriello,Domenico Galati,Antonio Ponticiello,A. Sanduzzi +12 more
TL;DR: IGRAs may be helpful for screening purposes in patient candidates for anti-TNF therapy to confirm positive TST results and in selected cases when false-negative results are suspected, and the utility of blood tests in patients with low or no TB risk remains to be assessed.
Journal ArticleDOI
Analysis of Mycobacterium tuberculosis-Specific CD8 T-Cells in Patients with Active Tuberculosis and in Individuals with Latent Infection
Nadia Caccamo,Giuliana Guggino,Serena Meraviglia,Giuseppe Gelsomino,Paola Di Carlo,Lucina Titone,Marialuisa Bocchino,Domenico Galati,Alessandro Matarese,Jan Nouta,Michèl R. Klein,Alfredo Salerno,Alessandro Sanduzzi,Francesco Dieli,Tom H. M. Ottenhoff +14 more
TL;DR: Different Mycobacterium tuberculosis specific CD8 T-cell phenotypic and functional signatures between subjects which control infection and those who do not (patients with active disease) are suggested.
Journal ArticleDOI
Efficacy of pirfenidone for idiopathic pulmonary fibrosis: An Italian real life study
Sergio Harari,A. Caminati,Carlo Albera,Carlo Vancheri,Venerino Poletti,Alberto Pesci,Fabrizio Luppi,Cesare Saltini,Carlo Agostini,Elena Bargagli,Alfredo Sebastiani,Alessandro Sanduzzi,Valeria Giunta,R. Della Porta,Gian Piero Bandelli,Silvia Puglisi,S. Tomassetti,Alice Biffi,Stefania Cerri,Alessia Mari,Francesco Cinetto,Francesca Tirelli,Gianfranco Farinelli,Marialuisa Bocchino,Claudia Specchia,Marco Confalonieri +25 more
TL;DR: Since pirfenidone provided significant treatment benefit for patients with moderate-severe disease, the results suggest that the drug may also be effective in patients with more advanced disease.