M
Mariana Palage
Researcher at Iuliu Hațieganu University of Medicine and Pharmacy
Publications - 20
Citations - 195
Mariana Palage is an academic researcher from Iuliu Hațieganu University of Medicine and Pharmacy. The author has contributed to research in topics: Isothermal titration calorimetry & Proton NMR. The author has an hindex of 6, co-authored 18 publications receiving 155 citations.
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Journal ArticleDOI
Food and Gastroesophageal Reflux Disease.
TL;DR: Current knowledge regarding food and gastroesophageal reflux is summarized and consistent data showed that a "short-meal-to-sleep interval" favors reflux episodes, therefore some authors recommend that dinner should be at least four hours before bedtime.
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COX Inhibition Profile and Molecular Docking Studies of Some 2-(Trimethoxyphenyl)-Thiazoles.
Smaranda Oniga,Liliana Pacureanu,Cristina Ioana Stoica,Mariana Palage,Alexandra M. Crăciun,Laurentiu Răzvan Rusu,Elena-Luminita Crisan,Cătălin Araniciu +7 more
TL;DR: The present data prove that the investigated compounds inhibit COX and thus confirm the previously reported in vivo anti-inflammatory screening results suggesting that A3 is a suitable candidate for further development as a NSAID.
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Adverse drug reactions detected by stimulated spontaneous reporting in an internal medicine department in Romania.
Andreea Farcas,Aura Sinpetrean,Cristina Mogosan,Mariana Palage,Oliviu Vostinaru,Marius Bojita,Dan L. Dumitrascu +6 more
TL;DR: Serious ADRs in hospitalized patients are common and often preventable, andequate training regarding pharmacology and optimization of drug therapy might help reduce ADRs' morbidity and mortality.
Journal ArticleDOI
New 2-Phenylthiazoles as Potential Sortase A Inhibitors: Synthesis, Biological Evaluation and Molecular Docking.
Smaranda Oniga,Cătălin Araniciu,Mariana Palage,Marcela Popa,Mariana Carmen Chifiriuc,Gabriel Marc,Adrian Pîrnău,Cristina Ioana Stoica,Ioannis Lagoudis,Theodoros Dragoumis,Ovidiu Oniga +10 more
TL;DR: A meta-analysis of structures known to act as Sortase A inhibitors provided the starting point for identifying a new potential scaffold that contain the 2-phenylthiazole moiety and synthesised a series of new compounds that prevent biofilm formation at very low concentrations.
Journal ArticleDOI
The Effect of Some 4,2 and 5,2 Bisthiazole Derivatives on Nitro-Oxidative Stress and Phagocytosis in Acute Experimental Inflammation
Cătălin Araniciu,Alina Elena Pârvu,Mariana Palage,Smaranda Oniga,Daniela Benedec,Ilioara Oniga,Ovidiu Oniga +6 more
TL;DR: Four of the bisthiazoles proved to have good anti-inflammatory properties, similar or superior to that of equal doses meloxicam, and improved serum oxidative status, when administered to rats with inflammation.