M
Mariarosaria Marinaro
Researcher at Istituto Superiore di Sanità
Publications - 52
Citations - 3316
Mariarosaria Marinaro is an academic researcher from Istituto Superiore di Sanità. The author has contributed to research in topics: Immune system & Antigen. The author has an hindex of 22, co-authored 52 publications receiving 3142 citations. Previous affiliations of Mariarosaria Marinaro include Osaka University & University of Alabama.
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Journal ArticleDOI
Probiotics Ameliorate Recurrent Th1-Mediated Murine Colitis by Inducing IL-10 and IL-10-Dependent TGF-β-Bearing Regulatory Cells
TL;DR: Probiotic (VSL#3) administration during a remission period ameliorates the severity of recurrent colitis by inducing an immunoregulatory response involving TGF-β-bearing regulatory cells.
Journal Article
Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4.
Mariarosaria Marinaro,Herman F. Staats,Takachika Hiroi,Raymond J. Jackson,Michel Coste,Prosper N. Boyaka,Nobuo Okahashi,M Yamamoto,Hiroshi Kiyono,Horst Bluethmann,Kohtaro Fujihashi,Jerry R. McGhee +11 more
TL;DR: Results show that CT acts as a mucosal adjuvant to enhance Th2-type responses and in particular, the IL-4 produced results in a characteristic Ab isotype pattern associated with this cytokine.
Journal ArticleDOI
Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse
Filippo Calcinaro,S. Dionisi,Mariarosaria Marinaro,Paola Candeloro,V. Bonato,Stefania Marzotti,R. B. Corneli,Elisabetta Ferretti,Alberto Gulino,F. Grasso,C. De Simone,U. Di Mario,Alberto Falorni,Monica Boirivant,Francesco Dotta,Francesco Dotta +15 more
TL;DR: Orally administered VSL#3 prevents autoimmune diabetes and induces immunomodulation by a reduction in insulitis severity, providing a sound rationale for future clinical trials of the primary prevention of type 1 diabetes by oral V SL#3 administration.
Journal ArticleDOI
Cholera toxin induces maturation of human dendritic cells and licences them for Th2 priming
Maria Cristina Gagliardi,Federica Sallusto,Mariarosaria Marinaro,Anja Langenkamp,Antonio Lanzavecchia,Maria Teresa De Magistris +5 more
TL;DR: It is found that CT induces phenotypic and functional maturation of blood monocyte‐derived DC, and the maturation program induced by CT is unique since CT does not induce but rather inhibits cytokine and chemokine secretion by lipopolysaccharide‐ or CD40 ligand‐activated DC.
Journal ArticleDOI
Mucosal immunity to infection with implications for vaccine development
Herman F. Staats,Herman F. Staats,Herman F. Staats,Raymond J. Jackson,Raymond J. Jackson,Raymond J. Jackson,Mariarosaria Marinaro,Mariarosaria Marinaro,Mariarosaria Marinaro,Ichiro Takahashi,Ichiro Takahashi,Ichiro Takahashi,Hiroshi Kiyono,Hiroshi Kiyono,Hiroshi Kiyono,Jerry R. McGhee,Jerry R. McGhee,Jerry R. McGhee +17 more
TL;DR: Novel vaccines and delivery systems are cited as being used to establish effective mucosal immunity against bacterial and viral diseases, including HIV, and systemic immunity.