M
Maricel G. Kann
Researcher at University of Maryland, Baltimore County
Publications - 56
Citations - 2028
Maricel G. Kann is an academic researcher from University of Maryland, Baltimore County. The author has contributed to research in topics: Gene & Protein domain. The author has an hindex of 23, co-authored 54 publications receiving 1809 citations. Previous affiliations of Maricel G. Kann include National Institutes of Health & University of Michigan.
Papers
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Histone structure and nucleosome stability
TL;DR: Recent findings on the structure of chromatin are reviewed that confirm previous interparticle interactions observed in crystal structures and influence DNA replication, transcription, repair and recombination.
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Chapter 4: Protein Interactions and Disease
Mileidy Gonzalez,Maricel G. Kann +1 more
TL;DR: The application of protein interaction networks as a translational approach to the study of human disease and the challenges faced by these approaches are described.
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Protein interactions and disease: computational approaches to uncover the etiology of diseases
TL;DR: This review explores recent approaches to the understanding of the mechanisms of disease at the molecular level through their underlying protein interactions through genetics, protein structure and protein interaction network analyses.
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Towards Precision Medicine: Advances in Computational Approaches for the Analysis of Human Variants
TL;DR: A detailed comparison of current human variant resources, including HGMD, OMIM, ClinVar, and UniProt/Swiss-Prot are provided, followed by an overview of the computational methods and techniques used to leverage the available data to predict novel deleterious variants.
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Advances in translational bioinformatics: computational approaches for the hunting of disease genes
TL;DR: This review highlights the latest advances in the field of translational bioinformatics, focusing on the advances of computational techniques to search for and classify disease genes.