M
Marie-Hélène Renalier
Researcher at Paul Sabatier University
Publications - 5
Citations - 162
Marie-Hélène Renalier is an academic researcher from Paul Sabatier University. The author has contributed to research in topics: Ribosomal RNA & Gene. The author has an hindex of 5, co-authored 5 publications receiving 159 citations.
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Journal ArticleDOI
U24, a novel intron-encoded small nucleolar RNA with two 12 nt long, phylogenetically conserved complementarities to 28S rRNA.
Liang-Hu Qu,Yves Henry,Monique Nicoloso,Bernard Michot,Marie-Claude Azum,Marie-Hélène Renalier,Michèle Caizergues-Ferrer,Jean-Pierre Bachellerie +7 more
TL;DR: Identification of the yeast Saccharomyces cerevisiae U24 gene directly confirms the outstanding conservation of the complementarity to 28S rRNA during evolution, suggesting a key role of U24 pairing to pre-rRNA during ribosome biogenesis, possible in the control of pre- rRNA folding.
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U21, a novel small nucleolar RNA with a 13 nt. complementarity to 28S rRNA, is encoded in an intron of ribosomal protein L5 gene in chicken and mammals
Liang-Hu Qu,Monique Nicoloso,Bernard Michot,Marie-Claude Azum,Michèle Caizergues-Ferrer,Marie-Hélène Renalier,Jean-Pierre Bachellerie +6 more
TL;DR: Sequence comparisons between chicken and mammals, together with Northern hybridizations with antisense oligonucleotides on cellular RNAs from more distant vertebrates, point to the preferential preservation of this segment of U21 sequence during evolution.
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Structure of the 5′-external transcribed spacer of the human ribosomal RNA gene
TL;DR: An outstanding secondary structure can be formed within the human ETS RNA, which could have a significant role in preribosome assembly and also apply to the other transcribed spacers of mammals indicating that a common and strong structural constraint is exerted on all these regions of the ribosomal gene.
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SnoRNA U21 is also intron-encoded in Drosophila melanogaster but in a different host-gene as compared to warm-blooded vertebrates
TL;DR: The characterization of Drosophila melanogaster homolog is reported, which is the first case of an intron‐encoded snoRNA in an invertebrate metazoan, pointing to an important role of the pairing of U21 to pre‐rRNA.
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Clones containing variant forms of complete human rRNA genes characterization and sequence of their transcription initiation region
TL;DR: In order to assess the extent of structural heterogeneity among ribosomal genes in the human genome, several cosmid clones, each containing an entire transcription unit, have been isolated and analyzed and point differences among the genes are observed.