M
Marie-Pierre Egloff
Researcher at University of Oxford
Publications - 2
Citations - 1089
Marie-Pierre Egloff is an academic researcher from University of Oxford. The author has contributed to research in topics: Phosphatase & Protein tyrosine phosphatase. The author has an hindex of 2, co-authored 2 publications receiving 1065 citations.
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Journal ArticleDOI
THE STRUCTURE AND MECHANISM OF PROTEIN PHOSPHATASES: Insights into Catalysis and Regulation
TL;DR: The crystal structures of a number ofprotein phosphatases have been determined, enabling us to understand their catalytic mechanisms and the basis for substrate recognition and to begin to provide insights into molecular mechanisms of protein phosphatase regulation.
Journal ArticleDOI
Crystal structure of the catalytic subunit of human protein phosphatase 1 and its complex with tungstate
Marie-Pierre Egloff,Patricia T.W. Cohen,Patricia T.W. Cohen,Patricia T.W. Cohen,Peter Reinemer,Peter Reinemer,Peter Reinemer,David Barford,David Barford,David Barford +9 more
TL;DR: The structure of PP1 provides insight into the molecular mechanism for substrate recognition, enzyme regulation and inhibition of this enzyme by toxins and tumour promoters and a basis for understanding the expanding family of related phosphatases which include PP2A and PP2B (calcineurin).