M
Mariella Chiricolo
Researcher at University of Bologna
Publications - 59
Citations - 1825
Mariella Chiricolo is an academic researcher from University of Bologna. The author has contributed to research in topics: Cell culture & Antigen. The author has an hindex of 25, co-authored 59 publications receiving 1700 citations. Previous affiliations of Mariella Chiricolo include University of Padua.
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Journal ArticleDOI
Sialyltransferases in cancer.
TL;DR: This review summarizes the current knowledge on the cancer-associated alterations in sialyltransferase expression which are often at the basis of the deranged expression of sIALylated structures.
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Mechanisms of cancer-associated glycosylation changes.
TL;DR: Some of the most relevant cancer-associated carbohydrate structures, including the β1,6-branching of N-linked chains, the sialyl Lewis antigens, the α2, 6-sialylated lactosamine, the Thomsen-Friedenreich-related antigen and gangliosides are discussed.
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Sialosignaling: sialyltransferases as engines of self-fueling loops in cancer progression.
TL;DR: It is shown that altered sialyltransferase expression in cancer, consequence of genetic and epigenetic alterations, generates a flow of information toward the membrane through the biosynthesis of aberrantly sialistic molecules, which can exacerbate the neoplastic phenotype.
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Glycosylation as a Main Regulator of Growth and Death Factor Receptors Signaling.
Inês Gomes Ferreira,Michela Pucci,Giulia Venturi,Nadia Malagolini,Mariella Chiricolo,Fabio Dall'Olio +5 more
TL;DR: A thorough picture is provided of the mechanisms by which glycosylation affects the activity of growth and death factor receptors in normal and pathological conditions and the development of next-generation drugs targeting glyco-epitopes of growth factor receptors should be considered a therapeutically interesting goal.
Journal Article
Deficiency of autologous mixed lymphocyte reactions and serum thymic factor level in Down's syndrome.
Claudio Franceschi,Federico Licastro,Mariella Chiricolo,F. Bonetti,Maria Zannotti,Nicola Fabris,Eugenio Mocchegiani,Mp Fantini,Paolo Paolucci,Massimo Masi +9 more
TL;DR: The hypothesis that a deficiency of the T-dependent regulatory system is an intrinsic feature of Down's syndrome is supported and the precocious aging of the immune system in these subjects is confirmed.