M
Mariko Ishiyama
Publications - 1
Citations - 25
Mariko Ishiyama is an academic researcher. The author has contributed to research in topics: Allosteric regulation & Fructose 1,6-bisphosphate. The author has an hindex of 1, co-authored 1 publications receiving 22 citations.
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An absolute requirement of fructose 1,6-bisphosphate for the Lactobacillus casei L-lactate dehydrogenase activity induced by a single amino acid substitution.
Kazuhito Arai,Atsushi Hishida,Mariko Ishiyama,Takeo Kamata,Hiroyuki Uchikoba,Shinya Fushinobu,Hiroshi Matsuzawa,Hayao Taguchi +7 more
TL;DR: The role of His205 in the allosteric regulation of the enzyme is discussed on the basis of the known crystal structures of L-LDHs, indicating that His205 is also largely involved in the pH-dependent sensitivity of L.casei L- LDH to Fru(1,6)P(2).