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Mariko Katoh

Researcher at University of Tsukuba

Publications -  17
Citations -  1085

Mariko Katoh is an academic researcher from University of Tsukuba. The author has contributed to research in topics: Dictyostelium & Dictyostelium discoideum. The author has an hindex of 13, co-authored 17 publications receiving 1050 citations. Previous affiliations of Mariko Katoh include Baylor College of Medicine.

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PCR-mediated generation of a gene disruption construct without the use of DNA ligase and plasmid vectors

TL;DR: This method depends on DNA fragment fusion by the PCR technique and requires only two steps of PCR to obtain a sufficient amount of the gene disruption construct for one transformation experiment, and is simple, rapid and relatively inexpensive.
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Polymorphic Members of the lag Gene Family Mediate Kin Discrimination in Dictyostelium

TL;DR: It is shown that lagB1 and lagC1 are highly polymorphic in natural populations and that their sequence dissimilarity correlates well with wild-strain segregation, revealing an early evolutionary origin of kin discrimination and providing insight into the mechanism of social recognition and immunity.
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Kin discrimination increases with genetic distance in a social amoeba.

TL;DR: It is demonstrated that D. discoideum cells co-aggregate more with genetically similar than dissimilar individuals, suggesting the existence of a mechanism that discerns the degree of genetic similarity between individuals in this social microorganism.
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A transcriptional profile of multicellular development in Dictyostelium discoideum.

TL;DR: Analysis of the two differentiated cell types, spores and stalk cells, and their precursors revealed a large number of differentially expressed genes as well as unexpected patterns of gene expression, which shed new light on the timing and possible mechanisms of cell-type divergence.
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Developmentally regulated DNA methylation in Dictyostelium discoideum.

TL;DR: A role for a Dnmt2 methyltransferase in eukaryotic development is established, indicating that DNA methylation has a regulatory role in Dictyostelium development.