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Marina Claro de Souza

Researcher at University of São Paulo

Publications -  7
Citations -  437

Marina Claro de Souza is an academic researcher from University of São Paulo. The author has contributed to research in topics: Drug delivery & Iontophoresis. The author has an hindex of 5, co-authored 7 publications receiving 347 citations.

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Liposomes as carriers of hydrophilic small molecule drugs: strategies to enhance encapsulation and delivery.

TL;DR: The rapidly increasing knowledge of the many overexpressed biochemical makers in pathological sites has enabled the development of liposomes decorated with ligands for cell-surface receptors and active delivery, resulting in an optimal therapeutic effect devoid of side effects.
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Skin cancer treatment effectiveness is improved by iontophoresis of EGFR-targeted liposomes containing 5-FU compared with subcutaneous injection.

TL;DR: Topical administration of immunoliposomes containing 5‐FU using iontophoresis is a promising strategy for SCC treatment and shows promise in reducing tumor aggressiveness and resulting in cells with less aggressive characteristics.
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Development of albendazole sulfoxide-loaded Eudragit microparticles: A potential strategy to improve the drug bioavailability

TL;DR: In this paper, the authors developed, physicochemical characterization, and in vitro release profile evaluation of ABZSO-loaded Eudragit RS PO® microparticles (MPs) in order to improve the rate of dissolution and the dissolved percentage of the drug in pH 7.4.
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Development of a Method to Evaluate the Release Profile of Tamoxifen from Pegylated Hybrid Micelles

TL;DR: The development and validation of a RP-HPLC method for the quantification of drug released from tamoxifen-loaded DSPE-PEG(2000)/TPGS micelles and the determination of the best dissolution medium and apparatus is described.
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NO Exchange for a Water Molecule Favorably Changes Iontophoretic Release of Ruthenium Complexes to the Skin.

TL;DR: The presence of Ru-NO in this skin layer suggests that further controlled release of NO can be achieved by photo-stimulation after iontophoresis, and its applicability as a tool in treating diverse skin diseases is assessed.