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Marinella Coco

Researcher at University of Catania

Publications -  92
Citations -  1564

Marinella Coco is an academic researcher from University of Catania. The author has contributed to research in topics: Athletes & Personality. The author has an hindex of 22, co-authored 84 publications receiving 1271 citations.

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The role of deep breathing on stress.

TL;DR: The results obtained from the present research support the possibility that deep breathing technique is capable to induce an effective improvement in mood and stress both in terms of self-reported evaluations (MPS and POMS) and of objective parameters, such as heart rate and salivary cortisol levels.
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Elevated blood lactate is associated with increased motor cortex excitability

TL;DR: It is hypothesized that in the motor cortex the lactate could have a protective role against fatigue, by hypothesizing that an increase of blood lactate is associated with a decrease of motor threshold, that is, an enhancement of motor cortex excitability.
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Treatment with rapamycin ameliorates clinical and histological signs of protracted relapsing experimental allergic encephalomyelitis in Dark Agouti rats and induces expansion of peripheral CD4+CD25+Foxp3+ regulatory T cells.

TL;DR: The data suggest that rapamycin has pharmacological potential worthy of consideration in the treatment of MS patients and that the milder course of the disease was associated with a reduction of the histopathological signs associated to EAE.
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Characterization of matrix metalloproteinase-2 and -9, ADAM-10 and N-cadherin expression in human glioblastoma multiforme

TL;DR: This study provides a comprehensive molecular portrayal of some of the major pathological hallmarks of GBM aggressiveness, which could be exploitable as potential targets for a new therapeutic approach.
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Sodium L-lactate differently affects brain-derived neurothrophic factor, inducible nitric oxide synthase, and heat shock protein 70 kDa production in human astrocytes and SH-SY5Y cultures.

TL;DR: It is proposed that sodium L‐lactate affects the expression of BDNF in SH‐SY5Y and astrocytes in a different manner: high levels of iNOS and NO expressed inSH‐SY 5Y have a profound inhibitory effect on the release of BD NF related to a more limited production of HSP70 by SH‐ SY5Y.