M
Mario Forcione
Researcher at University Hospitals Birmingham NHS Foundation Trust
Publications - 17
Citations - 208
Mario Forcione is an academic researcher from University Hospitals Birmingham NHS Foundation Trust. The author has contributed to research in topics: Concussion & Traumatic brain injury. The author has an hindex of 6, co-authored 15 publications receiving 110 citations. Previous affiliations of Mario Forcione include National Institute for Health Research & University of Birmingham.
Papers
More filters
Journal ArticleDOI
Salivary MicroRNAs: Diagnostic Markers of Mild Traumatic Brain Injury in Contact-Sport.
Valentina Di Pietro,Valentina Di Pietro,Valentina Di Pietro,Edoardo Porto,Edoardo Porto,Marco Ragusa,Cristina Barbagallo,David Davies,Mario Forcione,Ann Logan,Cinzia Di Pietro,Michele Purrello,Michael James Grey,Douglas Hammond,Vijay Sawlani,Aron K. Barbey,Antonio Belli,Antonio Belli +17 more
TL;DR: Saliva samples of concussed players were collected after 48–72 h from concussion and analyzed by high-throughput technologies and biocomputation analysis predicted the involvement of these microRNAs in important biological processes that might be related to trauma, such as response to hypoxia, cell death, neurogenesis, axon repair and myelination.
Journal ArticleDOI
Cerebral Oxygenation in Traumatic Brain Injury: Can a Non-Invasive Frequency Domain Near-Infrared Spectroscopy Device Detect Changes in Brain Tissue Oxygen Tension as Well as the Established Invasive Monitor?
David Davies,Michael Clancy,Hamid Dehghani,Samuel J. E. Lucas,Mario Forcione,Kamal M. Yakoub,Antonio Belli +6 more
TL;DR: A variable performance in the predictive powers of this FD-NIRS device to detect changes in brain tissue oxygen was demonstrated, and this enhanced NIRS technology has not demonstrated sufficient ability to replace the established invasive measurement.
Journal ArticleDOI
Frequency-domain vs continuous-wave near-infrared spectroscopy devices: a comparison of clinically viable monitors in controlled hypoxia
David Davies,Michael Clancy,Daniel Lighter,George M. Balanos,Samuel J. E. Lucas,Hamid Dehghani,Zhangjie Su,Zhangjie Su,Mario Forcione,Antonio Belli,Antonio Belli +10 more
TL;DR: The aim of this study was to compare the abilities of a continuous-wave NIRS device with a similarly clinically viable N IRS device utilising a frequency-domain parameter recovery technique in detecting changes in cerebral tissue saturation during stepwise increases of experimentally induced hypoxia.
Journal ArticleDOI
Cerebral perfusion and blood-brain barrier assessment in brain trauma using contrast-enhanced near-infrared spectroscopy with indocyanine green: A review.
Mario Forcione,Mario Forcione,Antonio Maria Chiarelli,David J Davies,David J Davies,David Perpetuini,Piotr Sawosz,Arcangelo Merla,Antonio Belli,Antonio Belli +9 more
TL;DR: The methods developed to monitor the brain perfusion and the blood–brain barrier integrity using the changes of diffuse reflectance during the ICG passage and the results on studies in animals and humans are described.
Journal ArticleDOI
Study of Concussion in Rugby Union through MicroRNAs (SCRUM): a study protocol of a prospective, observational cohort study.
Kamal M. Yakoub,Patrick O’Halloran,David Davies,Conor Bentley,Callum N. Watson,Mario Forcione,Ugo Scarpa,Jonathan R B Bishop,Emma Toman,Douglas Hammond,Matthew Cross,Keith Stokes,Simon Kemp,David K. Menon,Valentina Di Pietro,Antonio Belli +15 more
TL;DR: An Observational, prospective, multicentre cohort study recruiting between the 2017–2018 and 2018–2019 Rugby Union seasons to establish a panel of non-invasive MicroRNA biomarkers in urine and saliva for the rapid diagnosis of sports-related concussion and investigate the kinetics and clinical utility of these biomarker in assisting diagnostic, prognostic and return-to-play decisions.