M
Marito Araki
Researcher at Juntendo University
Publications - 68
Citations - 3674
Marito Araki is an academic researcher from Juntendo University. The author has contributed to research in topics: Essential thrombocythemia & Medicine. The author has an hindex of 22, co-authored 55 publications receiving 3375 citations. Previous affiliations of Marito Araki include Duke University & National University of Singapore.
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Journal ArticleDOI
The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta.
Chikahide Masutani,Rika Kusumoto,Rika Kusumoto,Ayumi Yamada,Naoshi Dohmae,Masayuki Yokoi,Mayumi Yuasa,Marito Araki,Shigenori Iwai,Koji Takio,Fumio Hanaoka +10 more
TL;DR: Recombinant human DNA polymerase η corrects the inability of XP-V cell extracts to carry out DNA replication by bypassing thymine dimers on damaged DNA, indicating that DNA polymerases η could be the XPV gene product.
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Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity.
Chikahide Masutani,Marito Araki,Ayumi Yamada,Rika Kusumoto,Rika Kusumoto,Tomokazu Nogimori,Takafumi Maekawa,Shigenori Iwai,Fumio Hanaoka +8 more
TL;DR: A sensitive assay system is established using an SV40 origin‐based plasmid to detect XP‐V complementation activity and isolated a protein from HeLa cells capable of complementing the defects inXP‐V cell extracts that corrected the translesion defects of extracts from three XPV cell strains.
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Centrosome Protein Centrin 2/Caltractin 1 Is Part of the Xeroderma Pigmentosum Group C Complex That Initiates Global Genome Nucleotide Excision Repair
Marito Araki,Chikahide Masutani,Mitsuyo Takemura,Akio Uchida,Kaoru Sugasawa,Jun Kondoh,Yoshiaki Ohkuma,Fumio Hanaoka +7 more
TL;DR: Findings suggest that the XPC-CEN2 interaction may reflect coupling of cell division and NER.
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Activation of the thrombopoietin receptor by mutant calreticulin in CALR-mutant myeloproliferative neoplasms
Marito Araki,Yinjie Yang,Nami Masubuchi,Yumi Hironaka,Hiraku Takei,Soji Morishita,Yoshihisa Mizukami,Shin Kan,Shuichi Shirane,Yoko Edahiro,Yoshitaka Sunami,Akimichi Ohsaka,Norio Komatsu +12 more
TL;DR: The expression of mutant but not wild-type CALR induces the thrombopoietin-independent growth of UT-7/TPO cells, and it is proposed that mutant CALR promotes myeloproliferative neoplasm development by activating c-MPL and its downstream pathway.
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ATP‐dependent chromatin remodeling facilitates nucleotide excision repair of UV‐induced DNA lesions in synthetic dinucleosomes
Kiyoe Ura,Marito Araki,Marito Araki,Hideaki Saeki,Chikahide Masutani,Takashi Ito,Shigenori Iwai,Toshimi Mizukoshi,Yasufumi Kaneda,Fumio Hanaoka +9 more
TL;DR: The results indicate that there is a functional connection between chromatin remodeling and the initiation step of NER, and provides direct evidence that the human NER machinery requires a space greater than the size of the linker DNA to excise UV lesions efficiently.