Mark A. Horsfield

TL;DR: An algorithm is presented that minimizes the bias inherent in making measurements with a fixed set of gradient vector directions by spreading out measurements in 3‐dimensional gradient vector space and this results in reduced scan times, increased precision, or improved resolution in diffusion tensor images.

TL;DR: In this article, the authors evaluated the pharmacodynamic effects of PTK/ZK by assessing changes in contrastenhancement parameters of metastatic liver lesions using dynamic contrastenhanced magnetic resonance imaging (DCE-MRI) in patients with advanced colorectal cancer treated in two ongoing, dose-escalating phase I studies.

TL;DR: A technique for assessing in vivo fiber connectivity in the human brain is presented that utilizes a novel connectivity algorithm that operates in three spatial dimensions and uses estimates of fiber tract orientation and tissue anisotropy to establish the pathways of fiber tracts.

TL;DR: DTI is able to identify MS lesions with severe tissue damage and to detect changes in the NAWM, indicating a role for DTI in monitoring advanced phases of the disease and indicating that DTI-derived measures are correlated with clinical disability.

TL;DR: The contribution that diffusion‐weighted imaging has made to the understanding of white matter diseases is critically appraised and the quantitative nature of diffusion MRI is one of its major attractions; however, this is offset by the more advanced hardware required to collect diffusion‐ Weighted images reliably, and the more complex processing to produce quantitative parametric diffusion images.