G
Graham R. Cherryman
Researcher at University of Leicester
Publications - 15
Citations - 1039
Graham R. Cherryman is an academic researcher from University of Leicester. The author has contributed to research in topics: Magnetic resonance imaging & Perfusion. The author has an hindex of 7, co-authored 15 publications receiving 1033 citations. Previous affiliations of Graham R. Cherryman include Leicester Royal Infirmary.
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Journal ArticleDOI
Dynamic Contrast-Enhanced Magnetic Resonance Imaging As a Biomarker for the Pharmacological Response of PTK787/ZK 222584, an Inhibitor of the Vascular Endothelial Growth Factor Receptor Tyrosine Kinases, in Patients With Advanced Colorectal Cancer and Liver Metastases: Results From Two Phase I Studies
Bruno Morgan,Anne L. Thomas,Joachim Drevs,Juergen Hennig,Martin Büchert,Asvina Jivan,Mark A. Horsfield,K. Mross,H. A. Ball,Lucy Lee,William Mietlowski,Stefan Fuxius,Clemens Unger,Kenneth J. O'Byrne,Andrew Henry,Graham R. Cherryman,Dirk Laurent,Margaret Dugan,Dieter Marmé,William P. Steward +19 more
TL;DR: In this article, the authors evaluated the pharmacodynamic effects of PTK/ZK by assessing changes in contrastenhancement parameters of metastatic liver lesions using dynamic contrastenhanced magnetic resonance imaging (DCE-MRI) in patients with advanced colorectal cancer treated in two ongoing, dose-escalating phase I studies.
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A myocardial perfusion reserve index in humans using first-pass contrast-enhanced magnetic resonance imaging.
James H. S. Cullen,Mark A. Horsfield,C.R. Reek,Graham R. Cherryman,David B. Barnett,Nilesh J. Samani +5 more
TL;DR: A myocardial perfusion reserve index derived from first-pass MRI studies can distinguish between normal subjects and patients with coronary artery disease and provides useful functional information on coronary lesions, particularly where the physiologic significance cannot be predicted accurately from the angiogram.
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Coronary artery disease: combined stress MR imaging protocol-one-stop evaluation of myocardial perfusion and function.
Penelope R. Sensky,Asvina Jivan,N. Hudson,Richard P. Keal,Bruno Morgan,J. Tranter,David P. de Bono,Nilesh J. Samani,Graham R. Cherryman +8 more
TL;DR: A dual stress magnetic resonance (MR) imaging protocol to evaluate myocardial perfusion, function, and hibernation was developed and tested and can be used to guide clinical management decisions regarding coronary artery revascularization procedures.
Journal ArticleDOI
DynamicT1Measurement Using Snapshot-FLASH MRI
TL;DR: The application of an inversion-recovery snapshot FLASH (fast low-angled shot) imaging sequence to the dynamic measurement of monoexponential T1 relaxation was investigated and there was a 10% difference between the T1 values when the approximate and exact solutions were used; this was statistically significant.
Journal ArticleDOI
Magnetic resonance perfusion imaging in patients with coronary artery disease: a qualitative approach.
TL;DR: Qualitative MRI analysis had high sensitivity and moderate specificity for detecting CA stenoses and has potential for de novo diagnosis of CAD and as a complementary modality to angiography to assess the significance of given angiographic lesions.