M
Mark A. Lipton
Researcher at Purdue University
Publications - 70
Citations - 2315
Mark A. Lipton is an academic researcher from Purdue University. The author has contributed to research in topics: Amino acid & Catalysis. The author has an hindex of 24, co-authored 70 publications receiving 2205 citations.
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Journal ArticleDOI
Conformations of cycloheptadecane. A comparison of methods for conformational searching
Martin Saunders,Kendall N. Houk,Yun-Dong Wu,W. Clark Still,Mark A. Lipton,George Chang,Wayne C. Guida +6 more
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Asymmetric Catalysis of the Strecker Amino Acid Synthesis by a Cyclic Dipeptide
TL;DR: In this paper, a cyclic dipeptide called cyclo[(S)-His-(S)-NorArg] has been prepared which catalyzes an enantioselective version of the Strecker amino acid synthesis.
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Facile and Efficient Guanylation of Amines Using Thioureas and Mukaiyama's Reagent
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"Concerted" transition state, stepwise mechanism. Dynamics effects in C2-C6 enyne allene cyclizations.
TL;DR: The C2-C6 (Schmittel)/ene cyclization of enyne-allenes is studied by a combination of kinetic isotope effects, theoretical calculations, and dynamics trajectories, and a consideration of dynamic effects is necessary to understand the mechanism.
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Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-κB
Soosung Kang,Muriel Cuendet,Denise Coutinho Endringer,Vicki L. Croy,John M. Pezzuto,Mark A. Lipton +5 more
TL;DR: A 78-membered library of resveratrol analogues in which the substituents on the two aryl rings and alkene were varied was synthesized using a solid-phase Wittig olefination reaction and contains inhibitors against all three proteins that were more potent than resver atrol itself.