accademiche [38]. Ada [45]. Adrian [45]. African [56]. Age [39, 49, 61]. Al [23]. Al-Rawi [23]. Aldous [68]. Alex [15]. Allure [46]. America [60, 66]. American [49, 69, 61, 52]. ancienne [25]. Andreas [28]. Angela [42]. Animals [16]. Ann [26]. Anna [19, 47]. Annotated [46]. Annotations [28]. Anti [37]. Anti-Copernican [37]. Antibiotic [64]. Anxiety [51]. Apocalyptic [61]. Archaeology [26]. Ark [36]. Artisan [32]. Asylum [48]. Atri [54]. Audra [65]. Australia [41]. Authorship [15]. Axelle [29].

/pdf/a-complete-bibliography-of-publications-in-isis-2000-2009-1nklqbzyfs.pdf

A Complete Bibliography of Publications in Isis, 2000{2009

Acute and enduring adverse effects of psilocybin have been reported anecdotally, but have not been well characterized. For this study, 1993 individuals (mean age 30 yrs; 78% male) completed an online survey about their single most psychologically difficult or challenging experience (worst "bad trip") after consuming psilocybin mushrooms. Thirty-nine percent rated it among the top five most challenging experiences of his/her lifetime. Eleven percent put self or others at risk of physical harm; factors increasing the likelihood of risk included estimated dose, duration and difficulty of the experience, and absence of physical comfort and social support. Of the respondents, 2.6% behaved in a physically aggressive or violent manner and 2.7% received medical help. Of those whose experience occurred >1 year before, 7.6% sought treatment for enduring psychological symptoms. Three cases appeared associated with onset of enduring psychotic symptoms and three cases with attempted suicide. Multiple regression analysis showed degree of difficulty was positively associated, and duration was negatively associated, with enduring increases in well-being. Difficulty of experience was positively associated with dose. Despite difficulties, 84% endorsed benefiting from the experience. The incidence of risky behavior or enduring psychological distress is extremely low when psilocybin is given in laboratory studies to screened, prepared, and supported participants.

Survey study of challenging experiences after ingesting psilocybin mushrooms: Acute and enduring positive and negative consequences.

Aims To determine the acute lethal toxicity of a range of psychoactive substances in terms of the dose customarily used as a single substance for non-medical purposes.

Design and method  A structured English-language literature search was conducted to identify experimental studies and clinical reports that documented human and non-human lethal doses of 20 abused substances that are distributed widely in Europe and North America. Four inclusion criteria were specified for the reports, and approximately 3000 relevant records were retrieved from search engines at Biosis, Science Citation Index, Google and the National Library of Medicine's Gateway. In order to account for different drug potencies, a ‘safety ratio’ was computed for each substance by comparing its reported acute lethal dose with the dose most commonly used for non-medical purposes.

Findings  The majority of published reports of acute lethal toxicity indicate that the decedent used a co-intoxicant (most often alcohol). The calculated safety ratios varied between substances by more than a factor of 100. Intravenous heroin appeared to have the greatest direct physiological toxicity; several hallucinogens appeared to have the least direct physiological toxicity.

Conclusions  Despite residual uncertainties, the substantial difference in safety ratios suggests that abused substances can be rank-ordered on the basis of their potential acute lethality.

https://rgable.files.wordpress.com/2012/02/toxicity-addiction-offprint2.pdf

Comparison of acute lethal toxicity of commonly abused psychoactive substances

Harm potential of magic mushroom use: A review

ion between fibre lignin and laccase in qualitative difference in temporal phases than laccase does alone. Resulting distinguished lignin modifications may have consequences for subsequent fibre behaviour (Barsberg 2002). Lund & Felby (2001) applied a range of mediators in laccase-modification of spruce and pine fibres and found ABTS and PPT (phenothiazine-10-propionic acid) to be effective in enhancing wet tensile strength of paper handsheets made from the pulp. Similar results were obtained with ABTS by Elegir et al. (2005, 2007). Treatment of fibres with laccase and gallic acid were also reported to change wet tensile strength (Chandra et al. 2004b), indicating that laccase-mediator system can influence properties of the fibre surfaces. Various mediators are therefore currently tested in MDF production with laccase in order to achieve higher reactivity between laccase and lignin and better board properties (Müller et al. 2006). The unfortunately limited availability of cheap and non-toxic mediators is of course a restricting factor in such approaches (Rochefort et al. 2004, Morozova et al. 2007). So far, in laccase-mediated bleaching of lignocellulosic fibres 1-hydroxybenzotriazole and the lignin-derived phenols acetosyringone and syringaldehyde acid have been positively tested as mediators whereas negligible effects were seen with p-coumaric acid (Ibarra et al. 2006, Camamero et al. 2007, Gutiérrez et al. 2007). Oppositional ABTS-mediated depolymerisation and polymerisation effects on kraft lignin samples (González Arzola et al. 2006, Hernández Fernaud et al. 2006) imply that the doses and times of mediators and enzymes applied have to be expected to play an important role in activating of fibre material. In line with this, dosages of 4-hydroxybenzoic acid were most influential in laccase-mediated modification of paper pulp (Chandra et al. 2004a). Further to applications of mediators to improve mechanical properties by laccase action, recent studies suggest that a successive xylanase and laccase treatment with or without mediators might also be useful in efficiently modifying fibre surfaces at least in paper production. As the gallic acid mediator treatment, successive xylanase-laccase treatment has been reported to increase the wet tensile strength of paper (Chandra & Raugaskas 2005, Kapoor et al. 2007). 2-component adhesives based on lignin and enzymes In the wood composite industry, addition of lignosulphonates (spent sulphite liquor) or kraft lignins from sulphate pulping, to conventional PF resins is targeted at replacing parts of the phenol component made from petrochemicals (e.g. see Roffael & Rauch 1971, Shen 1974, Nimz 1983, Ayla & Nimz 1984, Danielson & Simonson 1998a,b, Tejado et al. 2007; further reading in Chapter 16 of this book). Formaldehyde from the PF resin may act in such mixtures as a cross-linker between the reactive sites of the technical lignins and the synthetic phenol binder (Kuo et al. 1991, Vázquez et al. 1999, El Mansouri & Salvadó 2006, 2007). As first

/pdf/wood-production-wood-technology-and-biotechnological-impacts-5gpvoylcbz.pdf

Wood production, wood technology, and biotechnological impacts

Psychoactive mushroom use in Koh Samui and Koh Pha-Ngan, Thailand

A comprehensive review is presented of the recreational and accidental ingestion of psychoactive mushroooms in Australia and New Zealand; 15 recognized species are considered from Australia and eight from New Zealand. Common epithets, potency levels, and methods of ingestion are discussed. Legal aspects involving the use of these psychoactive fungi are noted. In addition, medical and psychoactive effects of these mushrooms and treatment for psilocybian mushroom poisoning are described. Numerous case reports, with commentary, are also presented.

An ethnomycological review of psychoactive agarics in Australia and New Zealand.

Identification of
 Cannabis
 Fiber from the Astana Cemeteries, Xinjiang, China, with Reference to Its Unique Decorative Utilization: In the Turpan District of Xinjiang, China, large numbers of ancient clay figurines, with representations including equestrians, animals, and actors, have been excavated from the Astana Cemeteries and date from about the 3rd to the 9th centuries C.E. Based on visual inspection, the tails of some of the figurines representing horses are made of plant fibers. Fourier Transform Infrared (FTIR) spectroscopy, light microscope examination, and drying–twist tests demonstrated that these fibers were extracted from one or more stalks of hemp (Cannabis) plants. This is a unique report of the utilization of Cannabis bast fibers for figurine decoration in ancient Turpan.

Identification of Cannabis Fiber from the Astana Cemeteries, Xinjiang, China, with Reference to Its Unique Decorative Utilization

The Green Republic. A Conservation History of Costa Rica

A well-preserved outer coffin, several hundred years old, was discovered under waterlogged conditions in the ancient Qian Zhang Tomb located within Wuxi, an old eastern Chinese city in southern part of Jiangsu Province. Wood anatomy was employed to identify the tree species used to build this ancient outer coffin. The results showed it was constructed of sturdy Chinese fir (Cunninghamia lanceolata). In addition, gas chromatography–mass spectrometry (GC-MS) was undertaken to examine the chemical composition of wood extract. The analysis indicates that cedrol, a sesquiterpene alcohol found in the essential oils, was the major compound of the extract and apparently a key factor responsible for the outstanding durability of this wood. A review of Chinese fir uses recorded in ancient Chinese literature is presented for historical context, along with a list of known archaeological sites that have contained remains of this conifer species in China. A hypothetical explanation for its selection as a coffin construction material by the noble family of Qian Zhang is also discussed.

Mark D. Merlin

Papers

Psychoactive mushroom use in Koh Samui and Koh Pha-Ngan, Thailand

An ethnomycological review of psychoactive agarics in Australia and New Zealand.

Identification of Cannabis Fiber from the Astana Cemeteries, Xinjiang, China, with Reference to Its Unique Decorative Utilization

The Green Republic. A Conservation History of Costa Rica

Wood Analysis of An Outer Coffin Unearthed From the Qian Zhang Tomb (Ad 1535) In Wuxi of East China