M
Mark D. Rollag
Researcher at Thomas Jefferson University
Publications - 60
Citations - 9114
Mark D. Rollag is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Melatonin & Pineal gland. The author has an hindex of 31, co-authored 60 publications receiving 8444 citations. Previous affiliations of Mark D. Rollag include Uniformed Services University of the Health Sciences.
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Book ChapterDOI
Mechanisms in the Eye that Mediate the Biological and Therapeutic Effects of Light in Humans
TL;DR: It is useful from both a scientific as well as a clinical perspective to establish the specific mechanisms in the eye which mediate the nonvisual therapeutic and biological effects of light.
Journal ArticleDOI
Randomized trial of polychromatic blue-enriched light for circadian phase shifting, melatonin suppression, and alerting responses.
John P. Hanifin,Steven W. Lockley,Kate S. Cecil,Kathleen E. West,Michael R. Jablonski,Benjamin Warfield,Mary E. James,Melissa A. Ayers,Brenda Byrne,Edward Gerner,Carissa Pineda,Mark D. Rollag,George C. Brainard +12 more
TL;DR: Blue-enriched light significantly improved subjective alertness but no differences were found for objective alertness, and these data contribute to the optimization of the short wavelength-en enriched spectra and intensities needed for circadian, neuroendocrine and neurobehavioral regulation.
Journal ArticleDOI
The Protein‐Phosphatase Inhibitor Okadaic Acid Mimics MSH‐Induced and Melatonin‐Reversible Melanosome Dispersion in Xenopus laevis Melanophores
Bruno Cozzi,Mark D. Rollag +1 more
TL;DR: The present study describes the ability of 315 nM okadaic acid to induce melanosome dispersion in cultured Xenopus laevis melanophores, indicating that a member of the protein-phosphatase 1 or 2A families must be active for maintenance of the aggregated state.
Journal ArticleDOI
Amphibian melanophores become photosensitive when treated with retinal
TL;DR: It is demonstrated that melanophore responses to light in vitro vary as a function of culture conditions and that retinal can activate melanophor photosensitivity.
Journal ArticleDOI
Ontogenetic development of S-antigen- and rod-opsin immunoreactions in retinal and pineal photoreceptors of Xenopus laevis in relation to the onset of melatonin-dependent color-change mechanisms.
TL;DR: The results indicate that in Xenopus laevis the molecular mechanisms of photoreception develop simultaneously in retina and pineal complex and the differentiation of phototransduction processes coincides with the onset of melatonin-dependent photoneuroendocrine regulation of color-change mechanisms.