M
Mark D. Rollag
Researcher at Thomas Jefferson University
Publications - 60
Citations - 9114
Mark D. Rollag is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Melatonin & Pineal gland. The author has an hindex of 31, co-authored 60 publications receiving 8444 citations. Previous affiliations of Mark D. Rollag include Uniformed Services University of the Health Sciences.
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Journal ArticleDOI
Melatonin regulation in humans with color vision deficiencies
Frederick L. Ruberg,Debra J. Skene,John P. Hanifin,Mark D. Rollag,Judie English,Josephine Arendt,George C. Brainard +6 more
TL;DR: It is suggested that a normal trichromatic visual system is not necessary for light-mediated neuroendocrine regulation in subjects with normal color vision.
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Sensitivity of adult male Djungarian hamsters (Phodopus sungorus sungorus) to melatonin injections throughout the day: effects on the reproductive system and the pineal.
TL;DR: There was no demonstrable effect of exogenous melatonin administration on the endogenous rhythm of pineal melatonin; the rhythm in injected hamsters was of identical duration and amplitude to that in uninjected controls on the same photoperiod.
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Ultraviolet regulation of neuroendocrine and circadian physiology in rodents.
George C. Brainard,Felix M. Barker,R.J. Hoffman,Milton H. Stetson,John P. Hanifin,P.L. Podolin,Mark D. Rollag +6 more
TL;DR: Results are consistent with the hypothesis that elements in the retina can transduce UV stimuli for circadian and neuroendocrine regulation and appear to be related to the degree of transmission through the ocular lens.
Journal ArticleDOI
MT-1 melatonin receptor expression increases the antiproliferative effect of melatonin on S-91 murine melanoma cells
Ana Luisa Kadekaro,Luciana Nogueira de Sousa Andrade,Lucile Maria Floeter-Winter,Mark D. Rollag,Victoria M. Virador,Wilfred D. Vieira,Ana Maria de Lauro Castrucci,Ana Maria de Lauro Castrucci +7 more
TL;DR: Melatonin treatment significantly inhibits S‐91 melanoma cell proliferation in vitro as well as reduces tumor growth in vivo, and expression of the MT‐1 melatonin receptor in melanoma cells is a potential alternative approach to specifically target cells in cancer therapeutic treatment.
Journal ArticleDOI
The suppression of nocturnal pineal melatonin in the Syrian hamster: dose-response curves at 500 and 360 nm.
TL;DR: The results demonstrate the importance of considering UV-A, in addition to the visible wavelengths, in the regulation of hamster pineal physiology, and show that the induction of a 50% depression of pineal melatonin requires 10 times the number of 360-nm photons compared to 500- nm photons at the level of the cornea.