M
Mark L. Andermann
Researcher at Beth Israel Deaconess Medical Center
Publications - 63
Citations - 7204
Mark L. Andermann is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Sensory system & Visual cortex. The author has an hindex of 31, co-authored 51 publications receiving 5884 citations. Previous affiliations of Mark L. Andermann include University of Pennsylvania & Harvard University.
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Journal ArticleDOI
Network anatomy and in vivo physiology of visual cortical neurons
Davi D. Bock,Wei-Chung Allen Lee,Aaron M. Kerlin,Mark L. Andermann,Greg Hood,Arthur W. Wetzel,Sergey Yurgenson,Edward R. Soucy,Hyon Suk Kim,R. Clay Reid +9 more
TL;DR: This work used two-photon calcium imaging to characterize a functional property—the preferred stimulus orientation—of a group of neurons in the mouse primary visual cortex and large-scale electron microscopy of serial thin sections was used to trace a portion of these neurons’ local network.
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Broadly Tuned Response Properties of Diverse Inhibitory Neuron Subtypes in Mouse Visual Cortex
TL;DR: The results suggest that the sensory responses of layer 2/3 GABAergic neurons reflect the pooled activity of the surrounding population--a principle that may generalize across species and sensory modalities.
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Coupling of total hemoglobin concentration, oxygenation, and neural activity in rat somatosensory cortex.
Anna Devor,Andrew K. Dunn,Mark L. Andermann,István Ulbert,István Ulbert,David A. Boas,Anders M. Dale +6 more
TL;DR: This first systematic study with sufficient statistical power to quantitatively characterize the relationship between changes in blood oxygen content and the neural spiking and synaptic activity shows there is a strongly nonlinear relationship between electrophysiological measures of neuronal activity and the hemodynamic response.
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Functional Specialization of Mouse Higher Visual Cortical Areas
TL;DR: Two-photon calcium imaging in awake mice is used to compare visual responses in primary visual cortex (V1) and in two downstream target areas, AL and PM, and it is predicted that area AL helps guide behaviors involving fast-moving stimuli, while area PM helps guide behavior involving slow-moving objects.
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Simultaneous imaging of total cerebral hemoglobin concentration, oxygenation, and blood flow during functional activation.
Andrew K. Dunn,Anna Devor,Hayrunnisa Bolay,Mark L. Andermann,Michael A. Moskowitz,Anders M. Dale,David A. Boas +6 more
TL;DR: The ability to image blood flow and hemoglobin concentration changes simultaneously with high resolution will permit detailed quantitative analysis of the spatiotemporal hemodynamics of functional brain activation, including imaging of oxygen metabolism.