Mark P. Dagleish

TL;DR: The apparent association of the four subpopulations of S. agalactiae with specific groups of host species suggests that some strains of aquatic S. gaelactiae may present a zoonotic or anthroponotic hazard.

TL;DR: Using the protein misfolding cyclic amplification (PMCA) technique, rabbits are no longer able to be classified as resistant to TSEs, demonstrating that leporids are not resistant to prion infection.

TL;DR: The results suggest that brain and tonsil harboured the same prion strain showing different glycoprofiles in relation to the different cellular/tissue types in which it replicated, and that a PrPSc-based estimate of scrapie infectivity in sheep tissues could be achieved by combining sensitive PrPres detection methods and bioassay in voles.

TL;DR: Accumulations of PrPd were observed in the rectal mucosa and other LRS tissues of VRQ/ARR sheep with preclinical and clinical scrapie, albeit with a lower frequency and magnitude than in sheep of other PrP genotypes.

TL;DR: In orally inoculated white-tailed deer, the presence of glycine (G) or serine (S) at codon 96 of the native PrP appeared to influence the temporal patterns of PrP(CWD) deposition, support further evaluation of rectal mucosa sampling in CWD surveillance.