M
Mark Poli
Researcher at United States Army Medical Research Institute of Infectious Diseases
Publications - 16
Citations - 433
Mark Poli is an academic researcher from United States Army Medical Research Institute of Infectious Diseases. The author has contributed to research in topics: Palytoxin & Brevetoxin. The author has an hindex of 12, co-authored 16 publications receiving 409 citations. Previous affiliations of Mark Poli include University of Trieste.
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Journal ArticleDOI
Stereostructure and Biological Activity of 42-Hydroxy-palytoxin: A New Palytoxin Analogue from Hawaiian Palythoa Subspecies
Patrizia Ciminiello,Carmela Dell'Aversano,Emma Dello Iacovo,Ernesto Fattorusso,Martino Forino,Laura Grauso,Luciana Tartaglione,Chiara Florio,Paola Lorenzon,Marco De Bortoli,Aurelia Tubaro,Mark Poli,Gary S. Bignami +12 more
TL;DR: Functional studies on this new palytoxin-like compound suggest that the new palitoxin analogue and palyToxin itself present similar biological activities.
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Distribution and elimination of brevetoxin PbTx-3 in rats
TL;DR: The distribution and elimination profile suggested that the liver was the major organ of metabolism and that biliary excretion was an important route of elimination, and Skeletal muscle does not appear to be a site of metabolism, but a storage compartment, from which toxin is slowly released prior to clearance by the liver.
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Sensitive and specific colorimetric ELISAs for Staphylococcus aureus enterotoxins A and B in urine and buffer
TL;DR: Simple, sensitive and accurate colorimetric capture ELISAs for staphylococcal enterotoxins A and B offer a viable, cost-effective method for analysis of these ubiquitous toxins and are ideal candidates for evaluating human exposure.
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Harmful dinoflagellate Ostreopsis cf. ovata Fukuyo: detection of ovatoxins in field samples and cell immunolocalization using antipalytoxin antibodies.
Giorgio Honsell,Marco De Bortoli,Sabrina Boscolo,Carmela Dell'Aversano,Cecilia Battocchi,Giampaolo Fontanive,Antonella Penna,Federico Berti,Silvio Sosa,Takeshi Yasumoto,Patrizia Ciminiello,Mark Poli,Aurelia Tubaro +12 more
TL;DR: Since harmful dinoflagellates do not always produce toxins, the immunocytochemical localization of ovatoxins, although qualitative, can provide an early warning for toxic Ostreopsis cells before their massive diffusion and/or concentration in seafood.
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Sanitary problems related to the presence of Ostreopsis spp. in the Mediterranean Sea: a multidisciplinary scientific approach
Giorgia Del Favero,Silvio Sosa,Marco Pelin,Elisabetta D'orlando,Chiara Florio,Paola Lorenzon,Mark Poli,Aurelia Tubaro +7 more
TL;DR: In response to the urgent need for toxicity characterization of palytoxin and its congeners, an integrated study encompassing both in vitro and in vivo methods was performed.