M
Markus Hohenfellner
Researcher at University Hospital Heidelberg
Publications - 134
Citations - 3635
Markus Hohenfellner is an academic researcher from University Hospital Heidelberg. The author has contributed to research in topics: Prostate cancer & Magnetic resonance imaging. The author has an hindex of 24, co-authored 134 publications receiving 2841 citations.
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Journal ArticleDOI
Diagnostic performance of 68Ga-PSMA-11 (HBED-CC) PET/CT in patients with recurrent prostate cancer: evaluation in 1007 patients.
Ali Afshar-Oromieh,Ali Afshar-Oromieh,Tim Holland-Letz,Frederik L. Giesel,Clemens Kratochwil,Walter Mier,Sabine Haufe,Nils Debus,Matthias Eder,Michael Eisenhut,Martin Schäfer,Oliver C. Neels,Markus Hohenfellner,Klaus Kopka,Hans-Ulrich Kauczor,Jürgen Debus,Uwe Haberkorn,Uwe Haberkorn +17 more
TL;DR: Tumour detection is clearly associated with PSA level and ADT and no associations were found between a pathological 68Ga-PSMA-11 PET/CT scan and patient age, amount of injected activity, PSADT or PSAVel.
Journal ArticleDOI
Targeted α-Therapy of Metastatic Castration-Resistant Prostate Cancer with 225Ac-PSMA-617: Swimmer-Plot Analysis Suggests Efficacy Regarding Duration of Tumor Control
Clemens Kratochwil,Frank Bruchertseifer,Hendrik Rathke,Markus Hohenfellner,Frederik L. Giesel,Uwe Haberkorn,Uwe Haberkorn,Alfred Morgenstern +7 more
TL;DR: A positive response for surrogate parameters demonstrates remarkable antitumor activity for 225Ac-PSMA-617 in a retrospectively analyzed group of patients, indicating a promising duration of tumor control, especially considering the unfavorable prognostic profile of the selected advanced-stage patients.
Journal ArticleDOI
Multiparametric Magnetic Resonance Imaging (MRI) and MRI–Transrectal Ultrasound Fusion Biopsy for Index Tumor Detection: Correlation with Radical Prostatectomy Specimen
Jan Philipp Radtke,Jan Philipp Radtke,Constantin Schwab,Maya B. Wolf,Martin T. Freitag,Céline D. Alt,Claudia Kesch,I. V. Popeneciu,C. Huettenbrink,Claudia Gasch,T. Klein,David Bonekamp,Stefan Duensing,Wilfried Roth,Svenja Schueler,Christian Stock,Heinz Peter Schlemmer,Matthias Roethke,Markus Hohenfellner,Boris Hadaschik +19 more
TL;DR: Multiparametric magnetic resonance imaging detects the index lesion accurately in 9 of 10 patients; however, the combined biopsy approach, while missing less significant cancer, comes at the cost of detecting more insignificant cancer.
Journal ArticleDOI
Critical Evaluation of Magnetic Resonance Imaging Targeted, Transrectal Ultrasound Guided Transperineal Fusion Biopsy for Detection of Prostate Cancer
Timur H. Kuru,Timur H. Kuru,Matthias Roethke,Jonas Seidenader,Tobias Simpfendörfer,S. Boxler,Khalid Alammar,Philip Rieker,Valentin Popeneciu,Wilfried Roth,Sascha Pahernik,Heinz Peter Schlemmer,Markus Hohenfellner,Boris Hadaschik +13 more
TL;DR: Since multiparametric magnetic resonance imaging still has some limitations, systematic biopsies should currently not be omitted and the morbidity of the transperineal saturation approach is reasonable and mainly self-limiting.
Journal ArticleDOI
Comparative analysis of transperineal template saturation prostate biopsy versus magnetic resonance imaging targeted biopsy with magnetic resonance imaging-ultrasound fusion guidance
Jan Philipp Radtke,Timur H. Kuru,Timur H. Kuru,S. Boxler,Céline D. Alt,I. V. Popeneciu,C. Huettenbrink,T. Klein,Sarah Steinemann,Claudia Bergstraesser,Matthias Roethke,Wilfried Roth,Heinz Peter Schlemmer,Markus Hohenfellner,Boris Hadaschik +14 more
TL;DR: Compared to systematic, transperineal biopsy as a reference test, magnetic resonance imaging targeted biopsy alone detected as many Gleason score 7 or greater tumors while simultaneously mitigating the detection of lower grade disease.