M
Markus Meissner
Researcher at Goethe University Frankfurt
Publications - 177
Citations - 2322
Markus Meissner is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Melanoma & Medicine. The author has an hindex of 22, co-authored 166 publications receiving 1757 citations. Previous affiliations of Markus Meissner include Karlsruhe Institute of Technology & University of Freiburg.
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Journal ArticleDOI
Impact of Different Spa Waters on Inflammation Parameters in Human Keratinocyte HaCaT Cells.
Nadja Zöller,Eva Maria Valesky,Matthias Hofmann,Jürgen Bereiter-Hahn,August Bernd,Roland Kaufmann,Markus Meissner,Stefan Kippenberger +7 more
TL;DR: It is shown that spa waters, and particularly those derived from thermal springs, reduce parameters associated with inflammation, and it seems likely that trace elements such as selenium and zinc are critical for the observed effects.
Journal ArticleDOI
Dimethylfumarate inhibits melanoma cell proliferation via p21 and p53 induction and bcl-2 and cyclin B1 downregulation
Irina Kaluzki,Igor Hrgovic,Tsige Hailemariam-Jahn,Monika Doll,Johannes Kleemann,Eva Maria Valesky,Stefan Kippenberger,Roland Kaufmann,Nadja Zoeller,Markus Meissner +9 more
TL;DR: Evidence is provided that DMF inhibits melanoma proliferation by reinduction of important cell cycle inhibitors leading to a concentration-dependent G0/G1 or G2/M cell cycle arrest and induction of apoptosis via downregulation of bcl-2 and inductionof p53 and PARP-1 cleavage.
Journal ArticleDOI
Inhibition of Rac1 GTPase downregulates vascular endothelial growth factor receptor-2 expression by suppressing Sp1-dependent DNA binding in human endothelial cells
Markus Meissner,Despina Michailidou,Despina Michailidou,Monika Stein,Igor Hrgovic,Roland Kaufmann,Jens Gille +6 more
TL;DR: It is shown that a dominant negative Rac1 expression vector led to a pronounced decrease in VEGFR2 mRNA and protein expression, and repression of the small Rho GTPase Rac1 seems to be an additional critical molecular mechanism in the regulation of V EGFR2 expression.
Journal ArticleDOI
Hedgehog pathway inhibitor in combination with radiation therapy for basal cell carcinomas of the head and neck First clinical experience with vismodegib for locally advanced disease
TL;DR: The combination of vismodegib and radiation seems feasible and the initial results are promising, and there was no increase in unexpected side effects in this cohort of patients.
Proceedings ArticleDOI
Automated constraint-driven topology synthesis for analog circuits
TL;DR: This contribution will present a fully automated approach for explorative topology synthesis of small analog circuit blocks through a parallelized industrial based sizing method, which shows the feasibility of this synthesis approach.