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Marlena S. Fejzo

Researcher at University of California, Los Angeles

Publications -  72
Citations -  3005

Marlena S. Fejzo is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Hyperemesis gravidarum & Pregnancy. The author has an hindex of 29, co-authored 62 publications receiving 2621 citations. Previous affiliations of Marlena S. Fejzo include Brigham and Women's Hospital & University of Southern California.

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Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains

TL;DR: It is demonstrated that HMGI-C, an architectural factor that functions in transcriptional regulation, has been disrupted by rearrangement at the 12q14-15 chromosomal breakpoint in lipomas, and a role for HM GI-C in adipogenesis and mesenchyme differentiation is suggested.
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Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo.

TL;DR: In vivo studies showed that the combination of lapatinib and trastuzumab had greater antitumor efficacy than either drug alone, and supports the ongoing clinical investigation of Lapatinib in patients with HER2-amplified disease.
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Frozen Tumor Tissue Microarray Technology for Analysis of Tumor RNA, DNA, and Proteins

TL;DR: OCT arrays work well for DNA, RNA, and protein analyses, and may have significant advantages over the original technology for the assessment of some genes and proteins by improving both qualitative and quantitative results.
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Characterization of Genes Encoding Known and Novel Human Mast Cell Tryptases on Chromosome 16p13.3

TL;DR: DNA blotting and restriction analysis suggest that the BACs include most members of the immediate tryptase family, and chromosome 16p13.3 harbors a cluster of known and previously undescribedMembers of the tryptases gene family.
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The psychosocial burden of hyperemesis gravidarum.

TL;DR: Over 80% of a large cohort of women with HG reported that HG caused a negative psychosocial impact, consisting of socioeconomic changes, job loss or difficulties, attitude changes including fear regarding future pregnancies and psychiatric sequelae.