A device for delivering a fluid to a patient, including an exit port, a dispenser for causing fluid from a reservoir to flow to the exit port, a local processor programmed to cause a flow of fluid to the exit port based on flow instructions from a separate, remote control device, and a wireless receiver connected to the local processor for receiving the flow instructions. The device also includes a housing free of user input components for providing flow instructions to the local processor, in order to reduce the complexity and costs of the device so that the device lends itself to being disposable in nature. A system and a kit are also described that include the fluid delivery device, a separate, remote control device, and accessories for transcutaneous delivery of fluid medications. Methods of utilizing the fluid delivery device to infuse fluid medications are additionally disclosed.

Devices, systems and methods for patient infusion

The present invention is directed to a drug delivery pump apparatus, which comprises: (a) an expandable and contractible enclosure having an interior volume that defines a medication reservoir; (b) one or more electroactive polymer actuators; (c) a medication outlet port providing fluid communication between the interior volume of the contractible and expandable enclosure and an exterior of the delivery pump apparatus; and (d) a control unit electrically coupled to the one or more actuators and sending control signals to the same. The one or more electroactive polymer actuators act to reduce the interior volume of the contractible and expandable enclosure based upon the received control signals. The present invention is also directed to a method of delivering a liquid therapeutic agent to a patient. The method comprises: (a) providing the above infusion pump apparatus; (b) placing the outlet port of the infusion pump apparatus in fluid communication with a patient; and (c) sending the control signals to the one or more actuators to reduce the internal volume of the contractible and expandable enclosure, thereby forcing a portion of the liquid therapeutic agent within the medication reservoir through the outlet port and into the patient.

Electroactive polymer actuated medication infusion pumps

A device (10) for delivering fluid including a disposable assembly (800) having an exit port assembly (70) and a metering portion of a dispenser (40) for controlling fluid flow to the exit port assembly (70), and a reusable assembly (700) having a control portion (46) of the dispenser (40) adapted to control the metering portion of the dispenser (40) upon attachment of the reusable assembly (700) and the disposable assembly (800), a local processor (50) connected to the dispenser (40) and programmed to cause fluid flow to the exit port assembly (70) through the dispenser (40) based upon flow instructions, and a local wireless communication element (60) connected to the local processor (50) for receiving flow instructions from a remote wireless device (100) The assemblies (700, 800) are adapted to be removably attached, and a power source (80) is contained in the disposable assembly (800) for providing power to the reusable assembly (700) upon attachment of the reusable assembly (700) and the disposable assembly (800)

Modular infusion device and method

A portable electronic device displays a plurality of icons (e.g., graphical objects) in a region in a touch-sensitive display; detects a predefined user action, with respect to the touch-sensitive display, for initiating a predefined user interface reconfiguration process; and varies positions of one or more icons in the plurality of icons in response to detecting the predefined user action. The varying includes varying the positions of the one or more icons about respective average positions.

Portable electronic device with interface reconfiguration mode

The present disclosure relates to bone cement formulations that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures together with cement injectors that include energy delivery systems for on-demand control of cement viscosity and flow parameters. The bone cement formulations may include a liquid component having at least one monomer and a non-liquid component including polymer particles and benzoyl peroxide (BPO). The non-liquid component may be further configured to allow controlled exposure of the BPO to the liquid monomer so as to enable control of the viscosity of the bone cement composition.

Bone treatment systems and methods

This invention is a syringe type apparatus which includes a unique fill assembly (18) for use in controllably injecting medicinal fluids into a patient. The filling assembly (18) includes a pre-filled vial (24) which is partially received within a novel adapter assembly (26) that functions to operably couple the pre-filled vial (24) with the syringe assembly (16) of the apparatus. The body of the pre-filled vial (24) is surrounded by a protective covering until immediately prior to mating the assembly with the syringe assembly (16).

Mixing and delivery syringe assembly

An apparatus for controllably intermixing two or more components in a sterile, closed environment to produce a flowable substance and then for expelling the flowable substance from the apparatus at a precisely controlled rate. The apparatus is particularly useful for medical applications and includes a dispenser portion with its own stored energy element provided in the form of an elastomeric membrane and a coupling mechanism for coupling a drug vial to the dispenser portion for controlled mixing a medicament contained within the drug vial with a diluent stored within the dispenser portion of the apparatus via a sterile pathway.

Closed drug delivery system

This invention is an apparatus (10) for accurately infusing fluids into a patient at specific rates over an extended period of time. The apparatus (10) is of a low profile, laminate or layered construction having a stored energy source in the form of a distended membrane (28), which in cooperation with the base (12) of the apparatus (10), defines one or more fluid reservoirs (20), each having a fluid inlet (22) and a fluid outlet (32). The apparatus further includes a novel conformable ullage made of yielding materials which uniquely conform to the shape of the elastomeric membrane (28) as the membrane (28) returns to its less distended configuration. This arrangement will satisfy even the most stringent medicament delivery tolerance requirements, and will elegantly overcome the limitations of materials selection encountered in devices embodying solely a rigid ullage construction. Additionally, in one form of the invention, the apparatus includes a novel fill assembly (302) for controllably filling the reservoirs of the device in the field.

Fluid delivery device with bolus injection site

This invention is a fluid delivery apparatus for continuous basal infusion, together with controlled bolus infusion of injectable medicaments, which embodies a stored energy source (66), such as distensible elastomeric membrane, which cooperates with a base and a conformable ullage to define a fluid reservoir.

Fluid delivery device with conformable ullage and fill assembly

An implantable fluid delivery apparatus for infusing medicinal fluids into a patient that includes a novel basal delivery system that includes a heat responsive polymer gel material which upon being heated by heater foil uniquely functions as an internal energy source for expelling basal doses of medicinal fluids from the device. The apparatus also includes a bolus delivery system that includes a magnetically responsive polymer gel which, upon being stimulated by an electro-magnet will delivery precise bolus doses of medicinal fluids to the patient.

Marshall S. Kriesel

Papers

Mixing and delivery syringe assembly

Closed drug delivery system

Fluid delivery device with bolus injection site

Fluid delivery device with conformable ullage and fill assembly

Implantable fluid delivery device for basal and bolus delivery of medicinal fluids