Marta Zapotoczna

TL;DR: These diverse biofilm mechanisms are reviewed, raise questions about why such redundancy exists, and outline potential implications for the development of new biofilm-targeted therapeutics are outlined.

TL;DR: Biofilms recovered from infected central venous catheters in a rat model of device-related infection were dispersed by nattokinase, supporting the important role of the biofilm phenotype and identifying a potentially new therapeutic approach with antimicrobials and fibrinolytic drugs, particularly during the early stages of device -related infection.

TL;DR: In this paper, a S. aureus mutant lacking the known platelet-activating surface proteins adhered directly to platelets in the absence of plasma proteins and triggered aggregation.

TL;DR: A novel role is reported for the well‐characterized iron‐regulated surface determinant B (IsdB) protein which is shown to promote adhesion of 293T, HeLa cells and platelets to immobilized bacteria independently of its ability to bind haemoglobin.

TL;DR: It is proposed that S. lugdunensis IsdB and IsdC proteins perform the same functions as those of S. aureus but, possibly due to its location, was less effective in its natural host.