where A represents the magnetic vector potential, is an integral of the hydromagnetic equations. This -integral made it possible to formulate a variational principle for the force-free magnetic fields. The integral expresses the fact that motions cannot transform a given field in an entirely arbitrary different field, if the conductivity of the medium isconsidered infinite. In this paper we shall show that the full set of hydromagnetic equations admit five more integrals, besides the energy integral, if dissipative processes are absent. These integrals, as we shall presently verify, are I2 =fbHvdV, (2)

Proceedings of the National Academy of Sciences

A new family of materials comprised of cellulose, cellulose nanomaterials (CNMs), having properties and functionalities distinct from molecular cellulose and wood pulp, is being developed for applications that were once thought impossible for cellulosic materials. Commercialization, paralleled by research in this field, is fueled by the unique combination of characteristics, such as high on-axis stiffness, sustainability, scalability, and mechanical reinforcement of a wide variety of materials, leading to their utility across a broad spectrum of high-performance material applications. However, with this exponential growth in interest/activity, the development of measurement protocols necessary for consistent, reliable and accurate materials characterization has been outpaced. These protocols, developed in the broader research community, are critical for the advancement in understanding, process optimization, and utilization of CNMs in materials development. This review establishes detailed best practices, methods and techniques for characterizing CNM particle morphology, surface chemistry, surface charge, purity, crystallinity, rheological properties, mechanical properties, and toxicity for two distinct forms of CNMs: cellulose nanocrystals and cellulose nanofibrils.

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Current characterization methods for cellulose nanomaterials

Journal of Magnetism and Magnetic Materials. Volumes 198-199, 1 June 1999,

The paper presents a critical overview on magnetic nanoparticles and microspheres used as separation media in different fields of chemistry, biochemistry, biology, and environment protection. The preparation of most widely used magnetic iron oxides in appropriate form, their coating or encapsulation in polymer microspheres, and functionalization is discussed in the first part. In the second part, new developments in the main application areas of magnetic composite particles for separation and catalytical purposes are briefly described. They cover separations and isolations of toxic inorganic and organic ions, proteins, and other biopolymers, cells, and microorganisms. Only selected number of relevant papers could be included due to the restricted extent of the review.

Preparation and properties of magnetic nano-and microsized particles for biological and environmental separations

소형 안테나 ( Small Antennas )

In this paper, a wireless interrogable sensor device based on an ultra low-power microcontroller for data collection and a radio frequency identification (RFID) interface for data transmission is presented. Wireless sensor systems utilizing RFID transponders offer a new and exciting means of measurement and identification suitable for many biomedical applications. For the majority of these applications, small, inexpensive radio request sensor systems are desirable. In this paper, an ultra-low-power and low-cost wireless temperature data logger system is presented with its application in observing dental retainer use. For this purpose, the retainer's ambient temperature is measured by an integrated sensor and recorded using a microcontroller which acts like a temperature data logger storing the thermal history of several months. For a self powered wireless data transmission from the sensor to the interrogation unit a RFID transponder, operating in the 13.56 MHz ISM band, is used. The presented sensor system includes hard- and software power saving modes reducing the sensor idle current consumption to 1 muA. This allows a battery powered operation of the device for up to two years. For dental and biomedical applications, the device is hermetically sealed using a biocompatible polymeric encapsulation. Results of the first clinical trials observing the patient's dental retainer usage by a set of retainers equipped with the RFID temperature sensor/data logger device are presented. The stored temperature values are analyzed and a clear temperature characteristic indicating the retainer usage was found.

A Low-Cost Wireless Sensor System and Its Application in Dental Retainers

Background: Citrate anticoagulation offers several advantages in comparison to conventional anticoagulation. Most algorithms for regional citrate-calcium anticoagulation are based on citrate and calcium chloride infusion coupled in a fixed proportion to the blood flow without considering the hematocrit (Hct)/plasma flow or the filter clearance of citrate and calcium. Methods: The aim of this study was to develop an algorithm for optimized citrate anticoagulation in extracorporeal therapies such as dialysis. A mathematical model was developed to calculate the volume of citrate infusion required to achieve a desired ionized calcium (iCa) target level in the extracorporeal circuit and to restore the total calcium level to a physiological value. Results: The model was validated by correlation analyses for different blood Hct values and shows an excellent fit to the laboratory measurements. Conclusion: The results for both iCa target concentrations, namely those after citrate and calcium infusion, proved that the software algorithm adapts well to variable treatment parameters.

A Target-Orientated Algorithm for Regional Citrate-Calcium Anticoagulation in Extracorporeal Therapies

Acute liver failure based on acute-on-chronic liver failure (AoCLF) or on acute severe damage of the liver caused by different etiologies includes complex mechanisms resulting in severe disturbances of principle liver functions. In order to compensate the liver's function of detoxification as efficiently as possible, fluidized bed absorbent systems have been designed. In these systems, small particles with specific adsorption properties for toxins related to acute liver failure are applied. A special technology based on adsorbents in suspension has been developed under the guidance of our group and is prepared for clinical application during the coming year. This technology is called microspheres-based detoxification system (MDS) and is based on microadsorbents with a diameter of 1-10 microm which are recirculated in suspension. The safety of the MDS is guaranteed by the use of fluorescently labeled magnetic microparticles, which in case of a membrane-leakage are detected in the blood circuit by an optical system equipped with a magnetic trap. In vitro tests with two kinds of microadsorbents (a combination of a hydrophobic neutral resin and an anion exchange resin) showed excellent efficiency of the system with respect to adsorption capacity as well as to the kinetics of elimination of albumin-bound substances (e.g. unconjugated bilirubin or cholic acid) and of non-protein-bound substances (e.g. phenol). Moreover, using a plasma filter or the Albuflow filter as membrane filters in the blood circuit, the MDS technology offers the possibility to remove inflammatory mediators such as tumor necrosis factor-alpha (TNF) by additional use of specific adsorbents.

Fluidized bed adsorbent systems for extracorporeal liver support.

Wireless Sensor Networks WSNs are becoming more important in the medical and environmental field. The authors propose an on-demand routing protocol using sensor attractiveness-metric Pa gradients for data forwarding decisions within the network. Attractiveness-based routing provides an efficient concept for data-centric routing in wireless sensor networks. The protocol works on-demand, is source-initiated, has a flat hierarchy and has its origin in the idea of pheromone-based routing. The algorithm supports node-to-sink data traffic and is therefore a lightweight approach to generalized multihop routing algorithms in WSNs. The performance evaluation of the proposed protocol is done by extensive simulation using a multi-agent based simulation environment called NetLogo. The efficiency of the attractiveness-based routing algorithm is compared in simulations with the well known Dynamic Source Routing algorithm DSR. The authors conclude that the Pabased routing algorithm is well suited for easy to set up WSNs because of its simplicity of implementation and its adaptability to different scenarios by adjustable weighting factors for the node's attractiveness metric.

A Source Based On-Demand Data Forwarding Scheme for Wireless Sensor Networks

The purpose of this study was to determine whether or not regional citrate anticoagulation (RCA) controlled by ionized calcium (iCa(2+)) would overcome thrombogenicity, prevent hemostasis, and complement activation during hemodialysis (HD). RCA was performed in 10 patients during 10 HD sessions using a polysulfone membrane in an effort to keep iCa(2+) at dialyzer outlet at < or =0.4 mmol/L. Compared to baseline, plasma levels of thrombin-antithrombin III complexes rose significantly at 240 min, and tissue factor and complement C5a component levels at 30 and 240 min of the procedure. Thrombocyte count declined significantly at 30 and 240 min, while activated clotting time (ACT) did not increase significantly, and platelet factor 4 as well as von Willebrand factor levels did not alter significantly. While ACT correlated significantly with some thrombogenicity markers, iCa(2+) did not correlate with ACT, changes in hemostasis, or C5a. We conclude the usually recommended iCa(2+) levels in the HD extracorporeal circuit did not guarantee the complete overcoming of thrombogenicity, prevention of hemostasis, and complement activation.

Martin Brandl

Papers

A Low-Cost Wireless Sensor System and Its Application in Dental Retainers

A Target-Orientated Algorithm for Regional Citrate-Calcium Anticoagulation in Extracorporeal Therapies

Fluidized bed adsorbent systems for extracorporeal liver support.

A Source Based On-Demand Data Forwarding Scheme for Wireless Sensor Networks

Citrate anticoagulation control by ionized calcium levels does not prevent hemostasis and complement activation during hemodialysis.